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Mitochondrial phosphatidylethanolamine modulates UCP1 to promote brown adipose thermogenesis.
Johnson JM, Peterlin AD, Balderas E, Sustarsic EG, Maschek JA, Lang MJ, Jara-Ramos A, Panic V, Morgan JT, Villanueva CJ, Sanchez A, Rutter J, Lodhi IJ, Cox JE, Fisher-Wellman KH, Chaudhuri D, Gerhart-Hines Z, Funai K. Johnson JM, et al. Among authors: maschek ja. Sci Adv. 2023 Feb 24;9(8):eade7864. doi: 10.1126/sciadv.ade7864. Epub 2023 Feb 24. Sci Adv. 2023. PMID: 36827367 Free PMC article.
Metabolic model for diversity-generating biosynthesis.
Tianero MD, Pierce E, Raghuraman S, Sardar D, McIntosh JA, Heemstra JR, Schonrock Z, Covington BC, Maschek JA, Cox JE, Bachmann BO, Olivera BM, Ruffner DE, Schmidt EW. Tianero MD, et al. Among authors: maschek ja. Proc Natl Acad Sci U S A. 2016 Feb 16;113(7):1772-7. doi: 10.1073/pnas.1525438113. Epub 2016 Feb 1. Proc Natl Acad Sci U S A. 2016. PMID: 26831074 Free PMC article.
Global Analysis of Plasma Lipids Identifies Liver-Derived Acylcarnitines as a Fuel Source for Brown Fat Thermogenesis.
Simcox J, Geoghegan G, Maschek JA, Bensard CL, Pasquali M, Miao R, Lee S, Jiang L, Huck I, Kershaw EE, Donato AJ, Apte U, Longo N, Rutter J, Schreiber R, Zechner R, Cox J, Villanueva CJ. Simcox J, et al. Among authors: maschek ja. Cell Metab. 2017 Sep 5;26(3):509-522.e6. doi: 10.1016/j.cmet.2017.08.006. Cell Metab. 2017. PMID: 28877455 Free PMC article.
Aspirin Suppresses PGE2 and Activates AMP Kinase to Inhibit Melanoma Cell Motility, Pigmentation, and Selective Tumor Growth In Vivo.
Kumar D, Rahman H, Tyagi E, Liu T, Li C, Lu R, Lum D, Holmen SL, Maschek JA, Cox JE, VanBrocklin MW, Grossman D. Kumar D, et al. Among authors: maschek ja. Cancer Prev Res (Phila). 2018 Oct;11(10):629-642. doi: 10.1158/1940-6207.CAPR-18-0087. Epub 2018 Jul 18. Cancer Prev Res (Phila). 2018. PMID: 30021726 Free PMC article.
Imbalanced sphingolipid signaling is maintained as a core proponent of a cancerous phenotype in spite of metabolic pressure and epigenetic drift.
Speirs MMP, Swensen AC, Chan TY, Jones PM, Holman JC, Harris MB, Maschek JA, Cox JE, Carson RH, Hill JT, Andersen JL, Prince JT, Price JC. Speirs MMP, et al. Among authors: maschek ja. Oncotarget. 2019 Jan 11;10(4):449-479. doi: 10.18632/oncotarget.26533. eCollection 2019 Jan 11. Oncotarget. 2019. PMID: 30728898 Free PMC article.
Energetic Trade-Offs and Hypometabolic States Promote Disease Tolerance.
Ganeshan K, Nikkanen J, Man K, Leong YA, Sogawa Y, Maschek JA, Van Ry T, Chagwedera DN, Cox JE, Chawla A. Ganeshan K, et al. Among authors: maschek ja. Cell. 2019 Apr 4;177(2):399-413.e12. doi: 10.1016/j.cell.2019.01.050. Epub 2019 Mar 7. Cell. 2019. PMID: 30853215 Free PMC article.
Targeting a ceramide double bond improves insulin resistance and hepatic steatosis.
Chaurasia B, Tippetts TS, Mayoral Monibas R, Liu J, Li Y, Wang L, Wilkerson JL, Sweeney CR, Pereira RF, Sumida DH, Maschek JA, Cox JE, Kaddai V, Lancaster GI, Siddique MM, Poss A, Pearson M, Satapati S, Zhou H, McLaren DG, Previs SF, Chen Y, Qian Y, Petrov A, Wu M, Shen X, Yao J, Nunes CN, Howard AD, Wang L, Erion MD, Rutter J, Holland WL, Kelley DE, Summers SA. Chaurasia B, et al. Among authors: maschek ja. Science. 2019 Jul 26;365(6451):386-392. doi: 10.1126/science.aav3722. Epub 2019 Jul 4. Science. 2019. PMID: 31273070 Free PMC article.
Mitochondrial PE potentiates respiratory enzymes to amplify skeletal muscle aerobic capacity.
Heden TD, Johnson JM, Ferrara PJ, Eshima H, Verkerke ARP, Wentzler EJ, Siripoksup P, Narowski TM, Coleman CB, Lin CT, Ryan TE, Reidy PT, de Castro Brás LE, Karner CM, Burant CF, Maschek JA, Cox JE, Mashek DG, Kardon G, Boudina S, Zeczycki TN, Rutter J, Shaikh SR, Vance JE, Drummond MJ, Neufer PD, Funai K. Heden TD, et al. Among authors: maschek ja. Sci Adv. 2019 Sep 11;5(9):eaax8352. doi: 10.1126/sciadv.aax8352. eCollection 2019 Sep. Sci Adv. 2019. PMID: 31535029 Free PMC article.
46 results