Mascelli M - Search Results

1

Pharmacokinetics of single and repeat doses of icatibant.

Leach JK, Spencer K, Mascelli M, McCauley TG. Leach JK, et al. Among authors: mascelli m. Clin Pharmacol Drug Dev. 2015 Mar;4(2):105-11. doi: 10.1002/cpdd.138. Epub 2015 Feb 2. Clin Pharmacol Drug Dev. 2015. PMID: 27128215 Clinical Trial.

2

Pharmacokinetics and bioavailability of a therapeutic enzyme (idursulfase) in cynomolgus monkeys after intrathecal and intravenous administration.

Xie H, Chung JK, Mascelli MA, McCauley TG. Xie H, et al. Among authors: mascelli ma. PLoS One. 2015 Apr 2;10(4):e0122453. doi: 10.1371/journal.pone.0122453. eCollection 2015. PLoS One. 2015. PMID: 25836678 Free PMC article.

3

Pharmacokinetics and safety of golimumab, a fully human anti-TNF-alpha monoclonal antibody, in subjects with rheumatoid arthritis.

Zhou H, Jang H, Fleischmann RM, Bouman-Thio E, Xu Z, Marini JC, Pendley C, Jiao Q, Shankar G, Marciniak SJ, Cohen SB, Rahman MU, Baker D, Mascelli MA, Davis HM, Everitt DE. Zhou H, et al. Among authors: mascelli ma. J Clin Pharmacol. 2007 Mar;47(3):383-96. doi: 10.1177/0091270006298188. J Clin Pharmacol. 2007. PMID: 17322150 Clinical Trial.

4

A phase I/II study of intrathecal idursulfase-IT in children with severe mucopolysaccharidosis II.

Muenzer J, Hendriksz CJ, Fan Z, Vijayaraghavan S, Perry V, Santra S, Solanki GA, Mascelli MA, Pan L, Wang N, Sciarappa K, Barbier AJ. Muenzer J, et al. Among authors: mascelli ma. Genet Med. 2016 Jan;18(1):73-81. doi: 10.1038/gim.2015.36. Epub 2015 Apr 2. Genet Med. 2016. PMID: 25834948 Free article. Clinical Trial.

5

A phase 1, double-blind, placebo-controlled study evaluating single subcutaneous administrations of a human interleukin-12/23 monoclonal antibody in subjects with plaque psoriasis.

Gottlieb AB, Cooper KD, McCormick TS, Toichi E, Everitt DE, Frederick B, Zhu Y, Pendley CE, Graham MA, Mascelli MA. Gottlieb AB, et al. Curr Med Res Opin. 2007 May;23(5):1081-92. doi: 10.1185/030079907x182112. Curr Med Res Opin. 2007. PMID: 17519075 Clinical Trial.

6

Molecular, biologic, and pharmacokinetic properties of monoclonal antibodies: impact of these parameters on early clinical development.

Mascelli MA, Zhou H, Sweet R, Getsy J, Davis HM, Graham M, Abernethy D. Mascelli MA, et al. J Clin Pharmacol. 2007 May;47(5):553-65. doi: 10.1177/0091270006298360. Epub 2007 Mar 22. J Clin Pharmacol. 2007. PMID: 17379759 Review.

7

Mechanisms of monoclonal antibody-drug interactions.

Zhou H, Mascelli MA. Zhou H, et al. Annu Rev Pharmacol Toxicol. 2011;51:359-72. doi: 10.1146/annurev-pharmtox-010510-100510. Annu Rev Pharmacol Toxicol. 2011. PMID: 20936946 Review.

8

A phase I study assessing the safety, clinical response, and pharmacokinetics of an experimental infliximab formulation for subcutaneous or intramuscular administration in patients with rheumatoid arthritis.

Westhovens R, Houssiau F, Joly J, Everitt DE, Zhu Y, Sisco D, Van Hartingsveldt B, Mascelli MA, Graham MA, Durez P, Bouman-Thio E. Westhovens R, et al. J Rheumatol. 2006 May;33(5):847-53. Epub 2006 Apr 1. J Rheumatol. 2006. PMID: 16583466 Clinical Trial.

9

Therapeutic targeting of the IL-12/23 pathways: generation and characterization of ustekinumab.

Benson JM, Sachs CW, Treacy G, Zhou H, Pendley CE, Brodmerkel CM, Shankar G, Mascelli MA. Benson JM, et al. Among authors: mascelli ma. Nat Biotechnol. 2011 Jul;29(7):615-24. doi: 10.1038/nbt.1903. Nat Biotechnol. 2011. PMID: 21747388

10

A phase I study evaluating the safety, pharmacokinetics, and clinical response of a human IL-12 p40 antibody in subjects with plaque psoriasis.

Kauffman CL, Aria N, Toichi E, McCormick TS, Cooper KD, Gottlieb AB, Everitt DE, Frederick B, Zhu Y, Graham MA, Pendley CE, Mascelli MA. Kauffman CL, et al. J Invest Dermatol. 2004 Dec;123(6):1037-44. doi: 10.1111/j.0022-202X.2004.23448.x. J Invest Dermatol. 2004. PMID: 15610511 Free article. Clinical Trial.

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