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N-(1'-naphthyl)-3,4,5-trimethoxybenzohydrazide as microtubule destabilizer: Synthesis, cytotoxicity, inhibition of cell migration and in vivo activity against acute lymphoblastic leukemia.
Salum LB, Mascarello A, Canevarolo RR, Altei WF, Laranjeira AB, Neuenfeldt PD, Stumpf TR, Chiaradia-Delatorre LD, Vollmer LL, Daghestani HN, de Souza Melo CP, Silveira AB, Leal PC, Frederico MJ, do Nascimento LF, Santos AR, Andricopulo AD, Day BW, Yunes RA, Vogt A, Yunes JA, Nunes RJ. Salum LB, et al. Among authors: mascarello a. Eur J Med Chem. 2015;96:504-18. doi: 10.1016/j.ejmech.2015.02.041. Epub 2015 Feb 23. Eur J Med Chem. 2015. PMID: 25951294
Antihyperglycemic activity of naphthylchalcones.
Damazio RG, Zanatta AP, Cazarolli LH, Chiaradia LD, Mascarello A, Nunes RJ, Yunes RA, Barreto Silva FR. Damazio RG, et al. Among authors: mascarello a. Eur J Med Chem. 2010 Apr;45(4):1332-7. doi: 10.1016/j.ejmech.2009.12.017. Epub 2009 Dec 16. Eur J Med Chem. 2010. PMID: 20061067
Inhibition of Mycobacterium tuberculosis tyrosine phosphatase PtpA by synthetic chalcones: kinetics, molecular modeling, toxicity and effect on growth.
Mascarello A, Chiaradia LD, Vernal J, Villarino A, Guido RV, Perizzolo P, Poirier V, Wong D, Martins PG, Nunes RJ, Yunes RA, Andricopulo AD, Av-Gay Y, Terenzi H. Mascarello A, et al. Bioorg Med Chem. 2010 Jun 1;18(11):3783-9. doi: 10.1016/j.bmc.2010.04.051. Epub 2010 Apr 21. Bioorg Med Chem. 2010. PMID: 20462762 Free article.
Trimethoxy-chalcone derivatives inhibit growth of Leishmania braziliensis: synthesis, biological evaluation, molecular modeling and structure-activity relationship (SAR).
Bello ML, Chiaradia LD, Dias LR, Pacheco LK, Stumpf TR, Mascarello A, Steindel M, Yunes RA, Castro HC, Nunes RJ, Rodrigues CR. Bello ML, et al. Among authors: mascarello a. Bioorg Med Chem. 2011 Aug 15;19(16):5046-52. doi: 10.1016/j.bmc.2011.06.023. Epub 2011 Jun 21. Bioorg Med Chem. 2011. PMID: 21757358
Activity of novel quinoxaline-derived chalcones on in vitro glioma cell proliferation.
Mielcke TR, Mascarello A, Filippi-Chiela E, Zanin RF, Lenz G, Leal PC, Chiaradia LD, Yunes RA, Nunes RJ, Battastini AM, Morrone FB, Campos MM. Mielcke TR, et al. Among authors: mascarello a. Eur J Med Chem. 2012 Feb;48:255-64. doi: 10.1016/j.ejmech.2011.12.023. Epub 2011 Dec 22. Eur J Med Chem. 2012. PMID: 22209415
51 results