Masakazu Kakuni - Search Results

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Results by year

Year	Number of Results
2002	2
2003	2
2006	1
2008	1
2010	1
2011	1
2012	4
2013	3
2014	1
2015	3
2016	2
2017	1
2018	2
2019	4
2020	3
2021	1
2022	2
2024	0

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Characterization and Prevention of Hypovitaminosis C in Chimeric Mice with Humanized Livers.

Touchette EK, Bates MC, Johnson MC, O'Brien TC, Melton RJ, Long KR, Kakuni M, Baginski M, Radiloff DR, Sagartz JE. Touchette EK, et al. Among authors: kakuni m. Comp Med. 2022 Dec 1;72(6):355-363. doi: 10.30802/AALAS-CM-22-000027. Comp Med. 2022. PMID: 36744513 Free PMC article.

Freshly Isolated Hepatocytes from Chimeric Humanized Liver Mice for the In Vitro Assessment of Drug Metabolism, Inhibition/Induction, and Safety Studies.

Kakuni M. Kakuni M. Curr Protoc. 2022 May;2(5):e429. doi: 10.1002/cpz1.429. Curr Protoc. 2022. PMID: 35598301

Identification of a novel long-acting 4'-modified nucleoside reverse transcriptase inhibitor against HBV.

Higashi-Kuwata N, Hayashi S, Kumamoto H, Ogata-Aoki H, Das D, Venzon D, Hattori SI, Bulut H, Hashimoto M, Otagiri M, Takamune N, Kishimoto N, Davis DA, Misumi S, Kakuni M, Tanaka Y, Mitsuya H. Higashi-Kuwata N, et al. Among authors: kakuni m. J Hepatol. 2021 May;74(5):1075-1086. doi: 10.1016/j.jhep.2020.12.006. Epub 2020 Dec 15. J Hepatol. 2021. PMID: 33333207 Free PMC article.

Predictability of human pharmacokinetics of drugs that undergo hepatic organic anion transporting polypeptide (OATP)-mediated transport using single-species allometric scaling in chimeric mice with humanized liver: integration with hepatic drug metabolism.

Sanoh S, Naritomi Y, Kitamura S, Shinagawa A, Kakuni M, Tateno C, Ohta S. Sanoh S, et al. Among authors: kakuni m. Xenobiotica. 2020 Nov;50(11):1370-1379. doi: 10.1080/00498254.2020.1769229. Epub 2020 Jun 5. Xenobiotica. 2020. PMID: 32401667

Lipoprotein profile and lipid metabolism of PXB-cells^®, human primary hepatocytes from liver-humanized mice: proposal of novel in vitro system for screening anti-lipidemic drugs.

Hata K, Sayaka T, Takahashi M, Sasaki A, Umekawa Y, Miyashita K, Ogura K, Toshima G, Maeda M, Takahashi J, Kakuni M. Hata K, et al. Among authors: kakuni m. Biomed Res. 2020;41(1):33-42. doi: 10.2220/biomedres.41.33. Biomed Res. 2020. PMID: 32092738 Free article.

Hepatic IFN-Induced Protein with Tetratricopeptide Repeats Regulation of HCV Infection.

Ishida Y, Kakuni M, Bang BR, Sugahara G, Lau DT, Tateno-Mukaidani C, Li M, Gale M Jr, Saito T. Ishida Y, et al. Among authors: kakuni m. J Interferon Cytokine Res. 2019 Mar;39(3):133-146. doi: 10.1089/jir.2018.0103. J Interferon Cytokine Res. 2019. PMID: 30844328 Free PMC article.

Chimeric mice with human hepatocytes: A new system for genotoxicity studies.

Tateno C, Fukumuro M, Masumori S, Kakuni M, Ishida Y, Shimada T, Hayashi M. Tateno C, et al. Among authors: kakuni m. Mutat Res Genet Toxicol Environ Mutagen. 2019 Mar;839:9-12. doi: 10.1016/j.mrgentox.2019.01.003. Epub 2019 Jan 14. Mutat Res Genet Toxicol Environ Mutagen. 2019. PMID: 30744813

Hepatitis B Virus Therapeutic Agent ARB-1740 Has Inhibitory Effect on Hepatitis Delta Virus in a New Dually-Infected Humanized Mouse Model.

Ye X, Tateno C, Thi EP, Kakuni M, Snead NM, Ishida Y, Barnard TR, Sofia MJ, Shimada T, Lee ACH. Ye X, et al. Among authors: kakuni m. ACS Infect Dis. 2019 May 10;5(5):738-749. doi: 10.1021/acsinfecdis.8b00192. Epub 2018 Nov 20. ACS Infect Dis. 2019. PMID: 30408957

Chimeric Mice With Humanized Livers Demonstrate Human-Specific Hepatotoxicity Caused by a Therapeutic Antibody Against TRAIL-Receptor 2/Death Receptor 5.

Nihira K, Nan-Ya KI, Kakuni M, Ono Y, Yoshikawa Y, Ota T, Hiura M, Yoshinari K. Nihira K, et al. Among authors: kakuni m. Toxicol Sci. 2019 Jan 1;167(1):190-201. doi: 10.1093/toxsci/kfy228. Toxicol Sci. 2019. PMID: 30202993

Organic Anion-Transporting Polypeptide (OATP)-Mediated Drug-Drug Interaction Study between Rosuvastatin and Cyclosporine A in Chimeric Mice with Humanized Liver.

Uchida M, Tajima Y, Kakuni M, Kageyama Y, Okada T, Sakurada E, Tateno C, Hayashi R. Uchida M, et al. Among authors: kakuni m. Drug Metab Dispos. 2018 Jan;46(1):11-19. doi: 10.1124/dmd.117.075994. Epub 2017 Oct 19. Drug Metab Dispos. 2018. PMID: 29051147

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