Marzinzik AL - Search Results

1

An efficient protocol for the solid-phase synthesis of malondiamides.

Vögtle MM, Marzinzik AL. Vögtle MM, et al. Among authors: marzinzik al. Molecules. 2005 Dec 31;10(12):1438-45. doi: 10.3390/10121438. Molecules. 2005. PMID: 18007540 Free PMC article.

2

Key Intermediates in Combinatorial Chemistry: Access to Various Heterocycles from alpha,beta-Unsaturated Ketones on the Solid Phase.

Marzinzik AL, Felder ER. Marzinzik AL, et al. J Org Chem. 1998 Feb 6;63(3):723-727. doi: 10.1021/jo971620u. J Org Chem. 1998. PMID: 11672066

3

Safe and reliable synthesis of diazoketones and quinoxalines in a continuous flow reactor.

Martin LJ, Marzinzik AL, Ley SV, Baxendale IR. Martin LJ, et al. Among authors: marzinzik al. Org Lett. 2011 Jan 21;13(2):320-3. doi: 10.1021/ol1027927. Epub 2010 Dec 16. Org Lett. 2011. PMID: 21162548

4

The Substrate-Activity-Screening methodology applied to receptor tyrosine kinases: a proof-of-concept study.

Chapelat J, Berst F, Marzinzik AL, Moebitz H, Drueckes P, Trappe J, Fabbro D, Seebach D. Chapelat J, et al. Among authors: marzinzik al. Eur J Med Chem. 2012 Nov;57:1-9. doi: 10.1016/j.ejmech.2012.08.038. Epub 2012 Sep 4. Eur J Med Chem. 2012. PMID: 23041456

5

Library design for fragment based screening.

Schuffenhauer A, Ruedisser S, Marzinzik AL, Jahnke W, Blommers M, Selzer P, Jacoby E. Schuffenhauer A, et al. Among authors: marzinzik al. Curr Top Med Chem. 2005;5(8):751-62. doi: 10.2174/1568026054637700. Curr Top Med Chem. 2005. PMID: 16101415 Review.

6

Identification of a PCSK9-LDLR disruptor peptide with in vivo function.

Brousseau ME, Clairmont KB, Spraggon G, Flyer AN, Golosov AA, Grosche P, Amin J, Andre J, Burdick D, Caplan S, Chen G, Chopra R, Ames L, Dubiel D, Fan L, Gattlen R, Kelly-Sullivan D, Koch AW, Lewis I, Li J, Liu E, Lubicka D, Marzinzik A, Nakajima K, Nettleton D, Ottl J, Pan M, Patel T, Perry L, Pickett S, Poirier J, Reid PC, Pelle X, Seepersaud M, Subramanian V, Vera V, Xu M, Yang L, Yang Q, Yu J, Zhu G, Monovich LG. Brousseau ME, et al. Cell Chem Biol. 2022 Feb 17;29(2):249-258.e5. doi: 10.1016/j.chembiol.2021.08.012. Epub 2021 Sep 20. Cell Chem Biol. 2022. PMID: 34547225 Free article.

7

Recent trends and observations in the design of high-quality screening collections.

Renner S, Popov M, Schuffenhauer A, Roth HJ, Breitenstein W, Marzinzik A, Lewis I, Krastel P, Nigsch F, Jenkins J, Jacoby E. Renner S, et al. Future Med Chem. 2011 Apr;3(6):751-66. doi: 10.4155/fmc.11.15. Future Med Chem. 2011. PMID: 21554080 Review.

8

Discovery of Novel Allosteric Non-Bisphosphonate Inhibitors of Farnesyl Pyrophosphate Synthase by Integrated Lead Finding.

Marzinzik AL, Amstutz R, Bold G, Bourgier E, Cotesta S, Glickman JF, Götte M, Henry C, Lehmann S, Hartwieg JC, Ofner S, Pellé X, Roddy TP, Rondeau JM, Stauffer F, Stout SJ, Widmer A, Zimmermann J, Zoller T, Jahnke W. Marzinzik AL, et al. ChemMedChem. 2015 Nov;10(11):1884-91. doi: 10.1002/cmdc.201500338. Epub 2015 Sep 18. ChemMedChem. 2015. PMID: 26381451

9

Towards intracellular delivery of peptides.

Marzinzik AL, Vorherr TE. Marzinzik AL, et al. Chimia (Aarau). 2013;67(12-13):899-904. doi: 10.2533/chimia.2013.899. Chimia (Aarau). 2013. PMID: 24594335 Free article.

10

Substrate profiling of IGF-1R and InsR: identification of a potent pentamer substrate.

Chapelat J, Berst F, Marzinzik AL, Moebitz H, Drueckes P, Fabbro D, Trappe J, Seebach D. Chapelat J, et al. Among authors: marzinzik al. Bioorg Med Chem Lett. 2011 Dec 1;21(23):7030-3. doi: 10.1016/j.bmcl.2011.09.101. Epub 2011 Sep 29. Bioorg Med Chem Lett. 2011. PMID: 22004721

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