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Melatonin is a potential drug for the prevention of bone loss during space flight.
Ikegame M, Hattori A, Tabata MJ, Kitamura KI, Tabuchi Y, Furusawa Y, Maruyama Y, Yamamoto T, Sekiguchi T, Matsuoka R, Hanmoto T, Ikari T, Endo M, Omori K, Nakano M, Yashima S, Ejiri S, Taya T, Nakashima H, Shimizu N, Nakamura M, Kondo T, Hayakawa K, Takasaki I, Kaminishi A, Akatsuka R, Sasayama Y, Nishiuchi T, Nara M, Iseki H, Chowdhury VS, Wada S, Ijiri K, Takeuchi T, Suzuki T, Ando H, Matsuda K, Somei M, Mishima H, Mikuni-Takagaki Y, Funahashi H, Takahashi A, Watanabe Y, Maeda M, Uchida H, Hayashi A, Kambegawa A, Seki A, Yano S, Shimazu T, Suzuki H, Hirayama J, Suzuki N. Ikegame M, et al. Among authors: maruyama y. J Pineal Res. 2019 Oct;67(3):e12594. doi: 10.1111/jpi.12594. Epub 2019 Jul 19. J Pineal Res. 2019. PMID: 31286565 Free PMC article.
Parathyroid hormone 1 (1-34) acts on the scales and involves calcium metabolism in goldfish.
Suzuki N, Danks JA, Maruyama Y, Ikegame M, Sasayama Y, Hattori A, Nakamura M, Tabata MJ, Yamamoto T, Furuya R, Saijoh K, Mishima H, Srivastav AK, Furusawa Y, Kondo T, Tabuchi Y, Takasaki I, Chowdhury VS, Hayakawa K, Martin TJ. Suzuki N, et al. Among authors: maruyama y. Bone. 2011 May 1;48(5):1186-93. doi: 10.1016/j.bone.2011.02.004. Epub 2011 Feb 17. Bone. 2011. PMID: 21334472 Free article.
Prostaglandin E₂ increases both osteoblastic and osteoclastic activity in the scales and participates in calcium metabolism in goldfish.
Omori K, Wada S, Maruyama Y, Hattori A, Kitamura K, Sato Y, Nara M, Funahashi H, Yachiguchi K, Hayakawa K, Endo M, Kusakari R, Yano S, Srivastav AK, Kusui T, Ejiri S, Chen W, Tabuchi Y, Furusawa Y, Kondo T, Sasayama Y, Nishiuchi T, Nakano M, Sakamoto T, Suzuki N. Omori K, et al. Among authors: maruyama y. Zoolog Sci. 2012 Aug;29(8):499-504. doi: 10.2108/zsj.29.499. Zoolog Sci. 2012. PMID: 22873807
Sardine procalcitonin amino-terminal cleavage peptide has a different action from calcitonin and promotes osteoblastic activity in the scales of goldfish.
Kase Y, Ikari T, Sekiguchi T, Sato M, Ogiso S, Kawada T, Matsubara S, Satake H, Sasayama Y, Endo M, Kitamura KI, Hattori A, Watanabe TX, Maruyama Y, Watanabe Y, Funahashi H, Kambegawa A, Suzuki N. Kase Y, et al. Among authors: maruyama y. Comp Biochem Physiol A Mol Integr Physiol. 2017 Sep;211:77-83. doi: 10.1016/j.cbpa.2017.06.007. Epub 2017 Jun 11. Comp Biochem Physiol A Mol Integr Physiol. 2017. PMID: 28614698
Circadian production of melatonin in cartilage modifies rhythmic gene expression.
Fu S, Kuwahara M, Uchida Y, Koudo S, Hayashi D, Shimomura Y, Takagaki A, Nishida T, Maruyama Y, Ikegame M, Hattori A, Kubota S, Hattori T. Fu S, et al. Among authors: maruyama y. J Endocrinol. 2019 Mar 1:JOE-19-0022.R2. doi: 10.1530/JOE-19-0022. Online ahead of print. J Endocrinol. 2019. PMID: 30889551 Free article.
Oral administration of melatonin contained in drinking water increased bone strength in naturally aged mice.
Igarashi-Migitaka J, Seki A, Ikegame M, Honda M, Sekiguchi T, Mishima H, Shimizu N, Matsubara H, Srivastav AK, Hirayama J, Maruyama Y, Kamijo-Ikemori A, Hirata K, Hattori A, Suzuki N. Igarashi-Migitaka J, et al. Among authors: maruyama y. Acta Histochem. 2020 Sep;122(6):151596. doi: 10.1016/j.acthis.2020.151596. Epub 2020 Jul 18. Acta Histochem. 2020. PMID: 32778234
2,381 results