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The CD44/COL17A1 pathway promotes the formation of multilayered, transformed epithelia.
Kozawa K, Sekai M, Ohba K, Ito S, Sako H, Maruyama T, Kakeno M, Shirai T, Kuromiya K, Kamasaki T, Kohashi K, Tanaka S, Ishikawa S, Sato N, Asano S, Suzuki H, Tanimura N, Mukai Y, Gotoh N, Tanino M, Tanaka S, Natsuga K, Soga T, Nakamura T, Yabuta Y, Saitou M, Ito T, Matsuura K, Tsunoda M, Kikumori T, Iida T, Mizutani Y, Miyai Y, Kaibuchi K, Enomoto A, Fujita Y. Kozawa K, et al. Among authors: maruyama t. Curr Biol. 2021 Jul 26;31(14):3086-3097.e7. doi: 10.1016/j.cub.2021.04.078. Epub 2021 Jun 3. Curr Biol. 2021. PMID: 34087104 Free article.
Rab5-regulated endocytosis plays a crucial role in apical extrusion of transformed cells.
Saitoh S, Maruyama T, Yako Y, Kajita M, Fujioka Y, Ohba Y, Kasai N, Sugama N, Kon S, Ishikawa S, Hayashi T, Yamazaki T, Tada M, Fujita Y. Saitoh S, et al. Among authors: maruyama t. Proc Natl Acad Sci U S A. 2017 Mar 21;114(12):E2327-E2336. doi: 10.1073/pnas.1602349114. Epub 2017 Mar 7. Proc Natl Acad Sci U S A. 2017. PMID: 28270608 Free PMC article.
Cell competition with normal epithelial cells promotes apical extrusion of transformed cells through metabolic changes.
Kon S, Ishibashi K, Katoh H, Kitamoto S, Shirai T, Tanaka S, Kajita M, Ishikawa S, Yamauchi H, Yako Y, Kamasaki T, Matsumoto T, Watanabe H, Egami R, Sasaki A, Nishikawa A, Kameda I, Maruyama T, Narumi R, Morita T, Sasaki Y, Enoki R, Honma S, Imamura H, Oshima M, Soga T, Miyazaki JI, Duchen MR, Nam JM, Onodera Y, Yoshioka S, Kikuta J, Ishii M, Imajo M, Nishida E, Fujioka Y, Ohba Y, Sato T, Fujita Y. Kon S, et al. Among authors: maruyama t. Nat Cell Biol. 2017 May;19(5):530-541. doi: 10.1038/ncb3509. Epub 2017 Apr 17. Nat Cell Biol. 2017. PMID: 28414314 Free article.
3,470 results