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Free fatty acids regulate insulin secretion from pancreatic beta cells through GPR40.
Itoh Y, Kawamata Y, Harada M, Kobayashi M, Fujii R, Fukusumi S, Ogi K, Hosoya M, Tanaka Y, Uejima H, Tanaka H, Maruyama M, Satoh R, Okubo S, Kizawa H, Komatsu H, Matsumura F, Noguchi Y, Shinohara T, Hinuma S, Fujisawa Y, Fujino M. Itoh Y, et al. Among authors: maruyama m. Nature. 2003 Mar 13;422(6928):173-6. doi: 10.1038/nature01478. Epub 2003 Feb 23. Nature. 2003. PMID: 12629551
FTBMT, a Novel and Selective GPR52 Agonist, Demonstrates Antipsychotic-Like and Procognitive Effects in Rodents, Revealing a Potential Therapeutic Agent for Schizophrenia.
Nishiyama K, Suzuki H, Harasawa T, Suzuki N, Kurimoto E, Kawai T, Maruyama M, Komatsu H, Sakuma K, Shimizu Y, Shimojo M. Nishiyama K, et al. Among authors: maruyama m. J Pharmacol Exp Ther. 2017 Nov;363(2):253-264. doi: 10.1124/jpet.117.242925. Epub 2017 Aug 29. J Pharmacol Exp Ther. 2017. PMID: 28851764
Identification of a G protein-coupled receptor specifically responsive to beta-alanine.
Shinohara T, Harada M, Ogi K, Maruyama M, Fujii R, Tanaka H, Fukusumi S, Komatsu H, Hosoya M, Noguchi Y, Watanabe T, Moriya T, Itoh Y, Hinuma S. Shinohara T, et al. Among authors: maruyama m. J Biol Chem. 2004 May 28;279(22):23559-64. doi: 10.1074/jbc.M314240200. Epub 2004 Mar 22. J Biol Chem. 2004. PMID: 15037633 Free article.
Anatomical transcriptome of G protein-coupled receptors leads to the identification of a novel therapeutic candidate GPR52 for psychiatric disorders.
Komatsu H, Maruyama M, Yao S, Shinohara T, Sakuma K, Imaichi S, Chikatsu T, Kuniyeda K, Siu FK, Peng LS, Zhuo K, Mun LS, Han TM, Matsumoto Y, Hashimoto T, Miyajima N, Itoh Y, Ogi K, Habata Y, Mori M. Komatsu H, et al. Among authors: maruyama m. PLoS One. 2014 Feb 28;9(2):e90134. doi: 10.1371/journal.pone.0090134. eCollection 2014. PLoS One. 2014. PMID: 24587241 Free PMC article.
1,603 results