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IGF-binding proteins secreted by cancer-associated fibroblasts induce context-dependent drug sensitization of lung cancer cells.
Remsing Rix LL, Sumi NJ, Hu Q, Desai B, Bryant AT, Li X, Welsh EA, Fang B, Kinose F, Kuenzi BM, Chen YA, Antonia SJ, Lovly CM, Koomen JM, Haura EB, Marusyk A, Rix U. Remsing Rix LL, et al. Among authors: marusyk a. Sci Signal. 2022 Aug 16;15(747):eabj5879. doi: 10.1126/scisignal.abj5879. Epub 2022 Aug 16. Sci Signal. 2022. PMID: 35973030 Free PMC article.
Resistance to targeted therapies as a multifactorial, gradual adaptation to inhibitor specific selective pressures.
Vander Velde R, Yoon N, Marusyk V, Durmaz A, Dhawan A, Miroshnychenko D, Lozano-Peral D, Desai B, Balynska O, Poleszhuk J, Kenian L, Teng M, Abazeed M, Mian O, Tan AC, Haura E, Scott J, Marusyk A. Vander Velde R, et al. Among authors: marusyk a, marusyk v. Nat Commun. 2020 May 14;11(1):2393. doi: 10.1038/s41467-020-16212-w. Nat Commun. 2020. PMID: 32409712 Free PMC article.
Measuring competitive exclusion in non-small cell lung cancer.
Farrokhian N, Maltas J, Dinh M, Durmaz A, Ellsworth P, Hitomi M, McClure E, Marusyk A, Kaznatcheev A, Scott JG. Farrokhian N, et al. Among authors: marusyk a. Sci Adv. 2022 Jul;8(26):eabm7212. doi: 10.1126/sciadv.abm7212. Epub 2022 Jul 1. Sci Adv. 2022. PMID: 35776787 Free PMC article.
Peristromal niches protect lung cancers from targeted therapies through a combined effect of multiple molecular mediators.
Desai B, Miti T, Prabhakaran S, Miroshnychenko D, Henry M, Marusyk V, Gatenbee C, Bui M, Scott J, Altrock PM, Haura E, Anderson ARA, Basanta D, Marusyk A. Desai B, et al. Among authors: marusyk a. bioRxiv [Preprint]. 2024 Apr 25:2024.04.24.590626. doi: 10.1101/2024.04.24.590626. bioRxiv. 2024. PMID: 38712093 Free PMC article. Preprint.
Spatial Proximity to Fibroblasts Impacts Molecular Features and Therapeutic Sensitivity of Breast Cancer Cells Influencing Clinical Outcomes.
Marusyk A, Tabassum DP, Janiszewska M, Place AE, Trinh A, Rozhok AI, Pyne S, Guerriero JL, Shu S, Ekram M, Ishkin A, Cahill DP, Nikolsky Y, Chan TA, Rimawi MF, Hilsenbeck S, Schiff R, Osborne KC, Letai A, Polyak K. Marusyk A, et al. Cancer Res. 2016 Nov 15;76(22):6495-6506. doi: 10.1158/0008-5472.CAN-16-1457. Epub 2016 Sep 26. Cancer Res. 2016. PMID: 27671678 Free PMC article.
53 results