Martins MA - Search Results

1

Design, Synthesis, Experimental and Theoretical Characterization of a New Multitarget 2-Thienyl-N-Acylhydrazone Derivative.

Bastos ITS, Pinheiro PSM, Costa FN, Rocha MD, Sant'Anna CMR, Braz D, Souza ET, Martins MA, Barreiro EJ, Ferreira FF, Barroso RC, Fraga CAM. Bastos ITS, et al. Among authors: martins ma. Pharmaceuticals (Basel). 2018 Nov 1;11(4):119. doi: 10.3390/ph11040119. Pharmaceuticals (Basel). 2018. PMID: 30388818 Free PMC article.

2

Evaluating the prophylactic potential of the phtalimide derivative LASSBio 552 on allergen-evoked inflammation in rats.

Neves JS, Lima LM, Fraga CA, Barreiro EJ, Miranda AL, Diaz BL, Balduino A, Siqueira Rde A, e Silva PM, Martins MA. Neves JS, et al. Among authors: martins ma. Eur J Pharmacol. 2005 Mar 28;511(2-3):219-27. doi: 10.1016/j.ejphar.2005.02.011. Eur J Pharmacol. 2005. PMID: 15792791

3

Design, synthesis, and pharmacological evaluation of N-acylhydrazones and novel conformationally constrained compounds as selective and potent orally active phosphodiesterase-4 inhibitors.

Kümmerle AE, Schmitt M, Cardozo SV, Lugnier C, Villa P, Lopes AB, Romeiro NC, Justiniano H, Martins MA, Fraga CA, Bourguignon JJ, Barreiro EJ. Kümmerle AE, et al. Among authors: martins ma. J Med Chem. 2012 Sep 13;55(17):7525-45. doi: 10.1021/jm300514y. Epub 2012 Aug 30. J Med Chem. 2012. PMID: 22891752

4

Synthesis and pharmacological evaluation of novel phenyl sulfonamide derivatives designed as modulators of pulmonary inflammatory response.

Barbosa ML, Ramos TJ, de Arantes AC, Martins MA, Silva PM, Barreiro EJ, Lima LM. Barbosa ML, et al. Among authors: martins ma. Molecules. 2012 Dec 10;17(12):14651-72. doi: 10.3390/molecules171214651. Molecules. 2012. PMID: 23222927 Free PMC article.

5

Synthesis, Pharmacological Profile and Docking Studies of New Sulfonamides Designed as Phosphodiesterase-4 Inhibitors.

Nunes IK, de Souza ET, Cardozo SV, Carvalho VF, Romeiro NC, Silva PM, Martins MA, Barreiro EJ, Lima LM. Nunes IK, et al. Among authors: martins ma. PLoS One. 2016 Oct 3;11(10):e0162895. doi: 10.1371/journal.pone.0162895. eCollection 2016. PLoS One. 2016. PMID: 27695125 Free PMC article.

6

LASSBio-897 Reduces Lung Injury Induced by Silica Particles in Mice: Potential Interaction with the A_2A Receptor.

Carvalho VF, Ferreira TPT, de Arantes ACS, Noël F, Tesch R, Sant'Anna CMR, Barreiro EJL, Fraga CAM, Rodrigues E Silva PM, Martins MA. Carvalho VF, et al. Among authors: martins ma. Front Pharmacol. 2017 Oct 31;8:778. doi: 10.3389/fphar.2017.00778. eCollection 2017. Front Pharmacol. 2017. PMID: 29163164 Free PMC article.

7

CCR5 Antagonist Maraviroc Inhibits Acute Exacerbation of Lung Inflammation Triggered by Influenza Virus in Cigarette Smoke-Exposed Mice.

Ferrero MR, Garcia CC, Dutra de Almeida M, Torres Braz da Silva J, Bianchi Reis Insuela D, Teixeira Ferreira TP, de Sá Coutinho D, Trindade de Azevedo C, Machado Rodrigues E Silva P, Martins MA. Ferrero MR, et al. Among authors: martins ma. Pharmaceuticals (Basel). 2021 Jun 28;14(7):620. doi: 10.3390/ph14070620. Pharmaceuticals (Basel). 2021. PMID: 34203121 Free PMC article.

8

Discovery of sulfonyl hydrazone derivative as a new selective PDE4A and PDE4D inhibitor by lead-optimization approach on the prototype LASSBio-448: In vitro and in vivo preclinical studies.

Nunes IKDC, de Souza ET, Martins IRR, Barbosa G, Moraes Junior MO, Medeiros MM, Silva SWD, Balliano TL, da Silva BA, Silva PMR, Carvalho VF, Martins MA, Lima LM. Nunes IKDC, et al. Among authors: martins ma, martins irr. Eur J Med Chem. 2020 Oct 15;204:112492. doi: 10.1016/j.ejmech.2020.112492. Epub 2020 Jul 18. Eur J Med Chem. 2020. PMID: 32717478

9

Gold Nanoparticles Inhibit Steroid-Insensitive Asthma in Mice Preserving Histone Deacetylase 2 and NRF2 Pathways.

Serra MF, Cotias AC, Pimentel AS, Arantes ACS, Pires ALA, Lanzetti M, Hickmann JM, Barreto E, Carvalho VF, Silva PMRE, Cordeiro RSB, Martins MA. Serra MF, et al. Among authors: martins ma. Antioxidants (Basel). 2022 Aug 26;11(9):1659. doi: 10.3390/antiox11091659. Antioxidants (Basel). 2022. PMID: 36139733 Free PMC article.

10

IL-13 immunotoxin accelerates resolution of lung pathological changes triggered by silica particles in mice.

Ferreira TP, de Arantes AC, do Nascimento CV, Olsen PC, Trentin PG, Rocco PR, Hogaboam CM, Puri RK, Martins MA, Silva PM. Ferreira TP, et al. Among authors: martins ma. J Immunol. 2013 Nov 15;191(10):5220-9. doi: 10.4049/jimmunol.1203551. Epub 2013 Oct 16. J Immunol. 2013. PMID: 24133168

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