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Enhancing nucleotide metabolism protects against mitochondrial dysfunction and neurodegeneration in a PINK1 model of Parkinson's disease.
Tufi R, Gandhi S, de Castro IP, Lehmann S, Angelova PR, Dinsdale D, Deas E, Plun-Favreau H, Nicotera P, Abramov AY, Willis AE, Mallucci GR, Loh SH, Martins LM. Tufi R, et al. Among authors: martins lm. Nat Cell Biol. 2014 Feb;16(2):157-66. doi: 10.1038/ncb2901. Epub 2014 Jan 19. Nat Cell Biol. 2014. PMID: 24441527 Free PMC article.
Mitochondrial dysfunction triggered by loss of HtrA2 results in the activation of a brain-specific transcriptional stress response.
Moisoi N, Klupsch K, Fedele V, East P, Sharma S, Renton A, Plun-Favreau H, Edwards RE, Teismann P, Esposti MD, Morrison AD, Wood NW, Downward J, Martins LM. Moisoi N, et al. Among authors: martins lm. Cell Death Differ. 2009 Mar;16(3):449-64. doi: 10.1038/cdd.2008.166. Epub 2008 Nov 21. Cell Death Differ. 2009. PMID: 19023330
Genetic analysis of mitochondrial protein misfolding in Drosophila melanogaster.
Pimenta de Castro I, Costa AC, Lam D, Tufi R, Fedele V, Moisoi N, Dinsdale D, Deas E, Loh SH, Martins LM. Pimenta de Castro I, et al. Among authors: martins lm. Cell Death Differ. 2012 Aug;19(8):1308-16. doi: 10.1038/cdd.2012.5. Epub 2012 Feb 3. Cell Death Differ. 2012. PMID: 22301916 Free PMC article.
Unravelling mitochondrial pathways to Parkinson's disease.
Celardo I, Martins LM, Gandhi S. Celardo I, et al. Among authors: martins lm. Br J Pharmacol. 2014 Apr;171(8):1943-57. doi: 10.1111/bph.12433. Br J Pharmacol. 2014. PMID: 24117181 Free PMC article. Review.
276 results