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Tumor-induced reshuffling of lipid composition on the endoplasmic reticulum membrane sustains macrophage survival and pro-tumorigenic activity.
Di Conza G, Tsai CH, Gallart-Ayala H, Yu YR, Franco F, Zaffalon L, Xie X, Li X, Xiao Z, Raines LN, Falquet M, Jalil A, Locasale JW, Percipalle P, Masson D, Huang SC, Martinon F, Ivanisevic J, Ho PC. Di Conza G, et al. Among authors: martinon f. Nat Immunol. 2021 Nov;22(11):1403-1415. doi: 10.1038/s41590-021-01047-4. Epub 2021 Oct 22. Nat Immunol. 2021. PMID: 34686867 Free PMC article.
AIM2 inflammasome is activated by pharmacological disruption of nuclear envelope integrity.
Di Micco A, Frera G, Lugrin J, Jamilloux Y, Hsu ET, Tardivel A, De Gassart A, Zaffalon L, Bujisic B, Siegert S, Quadroni M, Broz P, Henry T, Hrycyna CA, Martinon F. Di Micco A, et al. Among authors: martinon f. Proc Natl Acad Sci U S A. 2016 Aug 9;113(32):E4671-80. doi: 10.1073/pnas.1602419113. Epub 2016 Jul 26. Proc Natl Acad Sci U S A. 2016. PMID: 27462105 Free PMC article.
162 results