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Contribution of ADAMTS1 as a tumor suppressor gene in human breast carcinoma. Linking its tumor inhibitory properties to its proteolytic activity on nidogen-1 and nidogen-2.
Martino-Echarri E, Fernández-Rodríguez R, Rodríguez-Baena FJ, Barrientos-Durán A, Torres-Collado AX, Plaza-Calonge Mdel C, Amador-Cubero S, Cortés J, Reynolds LE, Hodivala-Dilke KM, Rodríguez-Manzaneque JC. Martino-Echarri E, et al. Int J Cancer. 2013 Nov 15;133(10):2315-24. doi: 10.1002/ijc.28271. Epub 2013 Jun 13. Int J Cancer. 2013. PMID: 23681936 Free article.
Stroma-derived but not tumor ADAMTS1 is a main driver of tumor growth and metastasis.
Fernández-Rodríguez R, Rodríguez-Baena FJ, Martino-Echarri E, Peris-Torres C, Del Carmen Plaza-Calonge M, Rodríguez-Manzaneque JC. Fernández-Rodríguez R, et al. Among authors: martino echarri e. Oncotarget. 2016 Jun 7;7(23):34507-19. doi: 10.18632/oncotarget.8922. Oncotarget. 2016. PMID: 27120788 Free PMC article.
Tumour angiogenesis is reduced in the Tc1 mouse model of Down's syndrome.
Reynolds LE, Watson AR, Baker M, Jones TA, D'Amico G, Robinson SD, Joffre C, Garrido-Urbani S, Rodriguez-Manzaneque JC, Martino-Echarri E, Aurrand-Lions M, Sheer D, Dagna-Bricarelli F, Nizetic D, McCabe CJ, Turnell AS, Kermorgant S, Imhof BA, Adams R, Fisher EM, Tybulewicz VL, Hart IR, Hodivala-Dilke KM. Reynolds LE, et al. Nature. 2010 Jun 10;465(7299):813-7. doi: 10.1038/nature09106. Nature. 2010. PMID: 20535211 Free PMC article.
12 results