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PI(3,4)P2-mediated cytokinetic abscission prevents early senescence and cataract formation.
Gulluni F, Prever L, Li H, Krafcikova P, Corrado I, Lo WT, Margaria JP, Chen A, De Santis MC, Cnudde SJ, Fogerty J, Yuan A, Massarotti A, Sarijalo NT, Vadas O, Williams RL, Thelen M, Powell DR, Schueler M, Wiesener MS, Balla T, Baris HN, Tiosano D, McDermott BM Jr, Perkins BD, Ghigo A, Martini M, Haucke V, Boura E, Merlo GR, Buchner DA, Hirsch E. Gulluni F, et al. Among authors: martini m. Science. 2021 Dec 10;374(6573):eabk0410. doi: 10.1126/science.abk0410. Epub 2021 Dec 10. Science. 2021. PMID: 34882480 Free PMC article.
PI3K keeps the balance between metabolism and cancer.
Braccini L, Ciraolo E, Martini M, Pirali T, Germena G, Rolfo K, Hirsch E. Braccini L, et al. Among authors: martini m. Adv Biol Regul. 2012 Sep;52(3):389-405. doi: 10.1016/j.jbior.2012.04.002. Epub 2012 Apr 24. Adv Biol Regul. 2012. PMID: 22884032 Review.
Targeting PI3K in Cancer: Any Good News?
Martini M, Ciraolo E, Gulluni F, Hirsch E. Martini M, et al. Front Oncol. 2013 May 8;3:108. doi: 10.3389/fonc.2013.00108. eCollection 2013. Front Oncol. 2013. PMID: 23658859 Free PMC article.
PI3K class II α controls spatially restricted endosomal PtdIns3P and Rab11 activation to promote primary cilium function.
Franco I, Gulluni F, Campa CC, Costa C, Margaria JP, Ciraolo E, Martini M, Monteyne D, De Luca E, Germena G, Posor Y, Maffucci T, Marengo S, Haucke V, Falasca M, Perez-Morga D, Boletta A, Merlo GR, Hirsch E. Franco I, et al. Among authors: martini m. Dev Cell. 2014 Mar 31;28(6):647-58. doi: 10.1016/j.devcel.2014.01.022. Dev Cell. 2014. PMID: 24697898 Free PMC article.
PI3K/AKT signaling pathway and cancer: an updated review.
Martini M, De Santis MC, Braccini L, Gulluni F, Hirsch E. Martini M, et al. Ann Med. 2014 Sep;46(6):372-83. doi: 10.3109/07853890.2014.912836. Epub 2014 Jun 5. Ann Med. 2014. PMID: 24897931 Review.
How PI3K-derived lipids control cell division.
Campa CC, Martini M, De Santis MC, Hirsch E. Campa CC, et al. Among authors: martini m. Front Cell Dev Biol. 2015 Sep 30;3:61. doi: 10.3389/fcell.2015.00061. eCollection 2015. Front Cell Dev Biol. 2015. PMID: 26484344 Free PMC article. Review.
Mitotic Spindle Assembly and Genomic Stability in Breast Cancer Require PI3K-C2α Scaffolding Function.
Gulluni F, Martini M, De Santis MC, Campa CC, Ghigo A, Margaria JP, Ciraolo E, Franco I, Ala U, Annaratone L, Disalvatore D, Bertalot G, Viale G, Noatynska A, Compagno M, Sigismund S, Montemurro F, Thelen M, Fan F, Meraldi P, Marchiò C, Pece S, Sapino A, Chiarle R, Di Fiore PP, Hirsch E. Gulluni F, et al. Among authors: martini m. Cancer Cell. 2017 Oct 9;32(4):444-459.e7. doi: 10.1016/j.ccell.2017.09.002. Cancer Cell. 2017. PMID: 29017056 Free article.
1,590 results