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SARS-CoV-2 replication in airway epithelia requires motile cilia and microvillar reprogramming.
Wu CT, Lidsky PV, Xiao Y, Cheng R, Lee IT, Nakayama T, Jiang S, He W, Demeter J, Knight MG, Turn RE, Rojas-Hernandez LS, Ye C, Chiem K, Shon J, Martinez-Sobrido L, Bertozzi CR, Nolan GP, Nayak JV, Milla C, Andino R, Jackson PK. Wu CT, et al. Cell. 2023 Jan 5;186(1):112-130.e20. doi: 10.1016/j.cell.2022.11.030. Epub 2022 Dec 2. Cell. 2023. PMID: 36580912 Free PMC article.
SARS-CoV-2 infection enhances mitochondrial PTP complex activity to perturb cardiac energetics.
Ramachandran K, Maity S, Muthukumar AR, Kandala S, Tomar D, Abd El-Aziz TM, Allen C, Sun Y, Venkatesan M, Madaris TR, Chiem K, Truitt R, Vishnu N, Aune G, Anderson A, Martinez-Sobrido L, Yang W, Stockand JD, Singh BB, Srikantan S, Reeves WB, Madesh M. Ramachandran K, et al. iScience. 2022 Jan 1;25(1):103722. doi: 10.1016/j.isci.2021.103722. eCollection 2022 Jan 21. iScience. 2022. PMID: 35005527 Free PMC article.
Mitigation of SARS-CoV-2 by Using Transition Metal Nanozeolites and Quaternary Ammonium Compounds as Antiviral Agents in Suspensions and Soft Fabric Materials.
Guerrero-Arguero I, Khan SR, Henry BM, Garcia-Vilanova A, Chiem K, Ye C, Shrestha S, Knight D, Cristner M, Hill S, Waldman WJ, Dutta PK, Torrelles JB, Martinez-Sobrido L, Nagy AM. Guerrero-Arguero I, et al. Int J Nanomedicine. 2023 May 3;18:2307-2324. doi: 10.2147/IJN.S396669. eCollection 2023. Int J Nanomedicine. 2023. PMID: 37163142 Free PMC article.
Anticancer pan-ErbB inhibitors reduce inflammation and tissue injury and exert broad-spectrum antiviral effects.
Saul S, Karim M, Ghita L, Huang PT, Chiu W, Durán V, Lo CW, Kumar S, Bhalla N, Leyssen P, Alem F, Boghdeh NA, Tran DH, Cohen CA, Brown JA, Huie KE, Tindle C, Sibai M, Ye C, Khalil AM, Chiem K, Martinez-Sobrido L, Dye JM, Pinsky BA, Ghosh P, Das S, Solow-Cordero DE, Jin J, Wikswo JP, Jochmans D, Neyts J, De Jonghe S, Narayanan A, Einav S. Saul S, et al. J Clin Invest. 2023 Oct 2;133(19):e169510. doi: 10.1172/JCI169510. J Clin Invest. 2023. PMID: 37581931 Free PMC article.
Extracellular Delivery of Functional Mitochondria Rescues the Dysfunction of CD4+ T Cells in Aging.
Headley CA, Gautam S, Olmo-Fontanez A, Garcia-Vilanova A, Dwivedi V, Akhter A, Schami A, Chiem K, Ault R, Zhang H, Cai H, Whigham A, Delgado J, Hicks A, Tsao PS, Gelfond J, Martinez-Sobrido L, Wang Y, Torrelles JB, Turner J. Headley CA, et al. Adv Sci (Weinh). 2024 Feb;11(5):e2303664. doi: 10.1002/advs.202303664. Epub 2023 Nov 21. Adv Sci (Weinh). 2024. PMID: 37990641 Free PMC article.
Plasmid-Based Lassa Virus Reverse Genetics.
Martínez-Sobrido L, Ye C, de la Torre JC. Martínez-Sobrido L, et al. Methods Mol Biol. 2024;2733:115-131. doi: 10.1007/978-1-0716-3533-9_8. Methods Mol Biol. 2024. PMID: 38064030
SARS-CoV-2 variants evolve convergent strategies to remodel the host response.
Bouhaddou M, Reuschl AK, Polacco BJ, Thorne LG, Ummadi MR, Ye C, Rosales R, Pelin A, Batra J, Jang GM, Xu J, Moen JM, Richards AL, Zhou Y, Harjai B, Stevenson E, Rojc A, Ragazzini R, Whelan MVX, Furnon W, De Lorenzo G, Cowton V, Syed AM, Ciling A, Deutsch N, Pirak D, Dowgier G, Mesner D, Turner JL, McGovern BL, Rodriguez ML, Leiva-Rebollo R, Dunham AS, Zhong X, Eckhardt M, Fossati A, Liotta NF, Kehrer T, Cupic A, Rutkowska M, Mena I, Aslam S, Hoffert A, Foussard H, Olwal CO, Huang W, Zwaka T, Pham J, Lyons M, Donohue L, Griffin A, Nugent R, Holden K, Deans R, Aviles P, Lopez-Martin JA, Jimeno JM, Obernier K, Fabius JM, Soucheray M, Hüttenhain R, Jungreis I, Kellis M, Echeverria I, Verba K, Bonfanti P, Beltrao P, Sharan R, Doudna JA, Martinez-Sobrido L, Patel AH, Palmarini M, Miorin L, White K, Swaney DL, Garcia-Sastre A, Jolly C, Zuliani-Alvarez L, Towers GJ, Krogan NJ. Bouhaddou M, et al. Cell. 2023 Oct 12;186(21):4597-4614.e26. doi: 10.1016/j.cell.2023.08.026. Epub 2023 Sep 21. Cell. 2023. PMID: 37738970
Aerosolized sulfated hyaluronan derivatives prolong the survival of K18 ACE2 mice infected with a lethal dose of SARS-CoV-2.
Pavan M, Fanti CD, Lucia AD, Canato E, Acquasaliente L, Sonvico F, Delgado J, Hicks A, Torrelles JB, Kulkarni V, Dwivedi V, Zanellato AM, Galesso D, Pasut G, Buttini F, Martinez-Sobrido L, Guarise C. Pavan M, et al. Eur J Pharm Sci. 2023 Aug 1;187:106489. doi: 10.1016/j.ejps.2023.106489. Epub 2023 Jun 11. Eur J Pharm Sci. 2023. PMID: 37311533 Free PMC article.
293 results