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Real-world evaluation of a novel technology for quantitative simultaneous antibody detection against multiple SARS-CoV-2 antigens in a cohort of patients presenting with COVID-19 syndrome.
Shaw AM, Hyde C, Merrick B, James-Pemberton P, Squires BK, Olkhov RV, Batra R, Patel A, Bisnauthsing K, Nebbia G, MacMahon E, Douthwaite S, Malim M, Neil S, Martinez Nunez R, Doores K, Mark TKI, Signell AW, Betancor G, Wilson HD, Galão RP, Pickering S, Edgeworth JD. Shaw AM, et al. Analyst. 2020 Aug 21;145(16):5638-5646. doi: 10.1039/d0an01066a. Epub 2020 Jul 8. Analyst. 2020. PMID: 32638712 Free PMC article.
Comparative assessment of multiple COVID-19 serological technologies supports continued evaluation of point-of-care lateral flow assays in hospital and community healthcare settings.
Pickering S, Betancor G, Galão RP, Merrick B, Signell AW, Wilson HD, Kia Ik MT, Seow J, Graham C, Acors S, Kouphou N, Steel KJA, Hemmings O, Patel A, Nebbia G, Douthwaite S, O'Connell L, Luptak J, McCoy LE, Brouwer P, van Gils MJ, Sanders RW, Martinez Nunez R, Bisnauthsing K, O'Hara G, MacMahon E, Batra R, Malim MH, Neil SJD, Doores KJ, Edgeworth JD. Pickering S, et al. PLoS Pathog. 2020 Sep 24;16(9):e1008817. doi: 10.1371/journal.ppat.1008817. eCollection 2020 Sep. PLoS Pathog. 2020. PMID: 32970782 Free PMC article.
Translational Research in the Time of COVID-19-Dissolving Boundaries.
Edgeworth JD, Batra R, Nebbia G, Bisnauthsing K, MacMahon E, Sudhanva M, Douthwaite S, Goldenberg S, O'Hara G, Shankar-Hari M, Doores KJ, Martinez-Nunez R, Hemsley C, Price NM, Lockett J, Lechler RI, Neil SJD, Malim MH. Edgeworth JD, et al. PLoS Pathog. 2020 Sep 30;16(9):e1008898. doi: 10.1371/journal.ppat.1008898. eCollection 2020 Sep. PLoS Pathog. 2020. PMID: 32997719 Free PMC article. No abstract available.
Longitudinal observation and decline of neutralizing antibody responses in the three months following SARS-CoV-2 infection in humans.
Seow J, Graham C, Merrick B, Acors S, Pickering S, Steel KJA, Hemmings O, O'Byrne A, Kouphou N, Galao RP, Betancor G, Wilson HD, Signell AW, Winstone H, Kerridge C, Huettner I, Jimenez-Guardeño JM, Lista MJ, Temperton N, Snell LB, Bisnauthsing K, Moore A, Green A, Martinez L, Stokes B, Honey J, Izquierdo-Barras A, Arbane G, Patel A, Tan MKI, O'Connell L, O'Hara G, MacMahon E, Douthwaite S, Nebbia G, Batra R, Martinez-Nunez R, Shankar-Hari M, Edgeworth JD, Neil SJD, Malim MH, Doores KJ. Seow J, et al. Nat Microbiol. 2020 Dec;5(12):1598-1607. doi: 10.1038/s41564-020-00813-8. Epub 2020 Oct 26. Nat Microbiol. 2020. PMID: 33106674 Free PMC article.
Recurrent emergence of SARS-CoV-2 spike deletion H69/V70 and its role in the Alpha variant B.1.1.7.
Meng B, Kemp SA, Papa G, Datir R, Ferreira IATM, Marelli S, Harvey WT, Lytras S, Mohamed A, Gallo G, Thakur N, Collier DA, Mlcochova P; COVID-19 Genomics UK (COG-UK) Consortium; Duncan LM, Carabelli AM, Kenyon JC, Lever AM, De Marco A, Saliba C, Culap K, Cameroni E, Matheson NJ, Piccoli L, Corti D, James LC, Robertson DL, Bailey D, Gupta RK. Meng B, et al. Cell Rep. 2021 Jun 29;35(13):109292. doi: 10.1016/j.celrep.2021.109292. Epub 2021 Jun 8. Cell Rep. 2021. PMID: 34166617 Free PMC article.
Resilient SARS-CoV-2 diagnostics workflows including viral heat inactivation.
Lista MJ, Matos PM, Maguire TJA, Poulton K, Ortiz-Zapater E, Page R, Sertkaya H, Ortega-Prieto AM, Scourfield E, O'Byrne AM, Bouton C, Dickenson RE, Ficarelli M, Jimenez-Guardeño JM, Howard M, Betancor G, Galao RP, Pickering S, Signell AW, Wilson H, Cliff P, Kia Ik MT, Patel A, MacMahon E, Cunningham E, Doores K, Agromayor M, Martin-Serrano J, Perucha E, Mischo HE, Shankar-Hari M, Batra R, Edgeworth J, Zuckerman M, Malim MH, Neil S, Martinez-Nunez RT. Lista MJ, et al. PLoS One. 2021 Sep 15;16(9):e0256813. doi: 10.1371/journal.pone.0256813. eCollection 2021. PLoS One. 2021. PMID: 34525109 Free PMC article.
Drug repurposing based on a quantum-inspired method versus classical fingerprinting uncovers potential antivirals against SARS-CoV-2.
Jimenez-Guardeño JM, Ortega-Prieto AM, Menendez Moreno B, Maguire TJA, Richardson A, Diaz-Hernandez JI, Diez Perez J, Zuckerman M, Mercadal Playa A, Cordero Deline C, Malim MH, Martinez-Nunez RT. Jimenez-Guardeño JM, et al. PLoS Comput Biol. 2022 Jul 18;18(7):e1010330. doi: 10.1371/journal.pcbi.1010330. eCollection 2022 Jul. PLoS Comput Biol. 2022. PMID: 35849631 Free PMC article.
SARS-CoV-2 evolution during treatment of chronic infection.
Kemp SA, Collier DA, Datir RP, Ferreira IATM, Gayed S, Jahun A, Hosmillo M, Rees-Spear C, Mlcochova P, Lumb IU, Roberts DJ, Chandra A, Temperton N; CITIID-NIHR BioResource COVID-19 Collaboration; COVID-19 Genomics UK (COG-UK) Consortium; Sharrocks K, Blane E, Modis Y, Leigh KE, Briggs JAG, van Gils MJ, Smith KGC, Bradley JR, Smith C, Doffinger R, Ceron-Gutierrez L, Barcenas-Morales G, Pollock DD, Goldstein RA, Smielewska A, Skittrall JP, Gouliouris T, Goodfellow IG, Gkrania-Klotsas E, Illingworth CJR, McCoy LE, Gupta RK. Kemp SA, et al. Nature. 2021 Apr;592(7853):277-282. doi: 10.1038/s41586-021-03291-y. Epub 2021 Feb 5. Nature. 2021. PMID: 33545711 Free PMC article.
49 results