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Mapping Determinants of Cytokine Signaling via Protein Engineering.
Gorby C, Martinez-Fabregas J, Wilmes S, Moraga I. Gorby C, et al. Among authors: martinez fabregas j. Front Immunol. 2018 Sep 27;9:2143. doi: 10.3389/fimmu.2018.02143. eCollection 2018. Front Immunol. 2018. PMID: 30319612 Free PMC article. Review.
IL-2 is inactivated by the acidic pH environment of tumors enabling engineering of a pH-selective mutein.
Gaggero S, Martinez-Fabregas J, Cozzani A, Fyfe PK, Leprohon M, Yang J, Thomasen FE, Winkelmann H, Magnez R, Conti AG, Wilmes S, Pohler E, van Gijsel Bonnello M, Thuru X, Quesnel B, Soncin F, Piehler J, Lindorff-Larsen K, Roychoudhuri R, Moraga I, Mitra S. Gaggero S, et al. Among authors: martinez fabregas j. Sci Immunol. 2022 Dec 9;7(78):eade5686. doi: 10.1126/sciimmunol.ade5686. Epub 2022 Dec 2. Sci Immunol. 2022. PMID: 36459543
Structural and functional analysis of novel human cytochrome C targets in apoptosis.
Martínez-Fábregas J, Díaz-Moreno I, González-Arzola K, Janocha S, Navarro JA, Hervás M, Bernhardt R, Velázquez-Campoy A, Díaz-Quintana A, De la Rosa MA. Martínez-Fábregas J, et al. Mol Cell Proteomics. 2014 Jun;13(6):1439-56. doi: 10.1074/mcp.M113.034322. Epub 2014 Mar 18. Mol Cell Proteomics. 2014. PMID: 24643968 Free PMC article.
PD-1 Inhibitory Receptor Downregulates Asparaginyl Endopeptidase and Maintains Foxp3 Transcription Factor Stability in Induced Regulatory T Cells.
Stathopoulou C, Gangaplara A, Mallett G, Flomerfelt FA, Liniany LP, Knight D, Samsel LA, Berlinguer-Palmini R, Yim JJ, Felizardo TC, Eckhaus MA, Edgington-Mitchell L, Martinez-Fabregas J, Zhu J, Fowler DH, van Kasteren SI, Laurence A, Bogyo M, Watts C, Shevach EM, Amarnath S. Stathopoulou C, et al. Among authors: martinez fabregas j. Immunity. 2018 Aug 21;49(2):247-263.e7. doi: 10.1016/j.immuni.2018.05.006. Epub 2018 Jul 24. Immunity. 2018. PMID: 30054205 Free PMC article.
14 results