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Hit-to-lead optimization of a 2-aminobenzimidazole series as new candidates for chagas disease.
de Oliveira Rezende Júnior C, Martinez PDG, Ferreira RAA, Koovits PJ, Miranda Soares B, Ferreira LLG, Michelan-Duarte S, Chelucci RC, Andricopulo AD, Matheeussen A, Van Pelt N, Caljon G, Maes L, Campbell S, Kratz JM, Mowbray CE, Dias LC. de Oliveira Rezende Júnior C, et al. Among authors: martinez pdg. Eur J Med Chem. 2023 Jan 15;246:114925. doi: 10.1016/j.ejmech.2022.114925. Epub 2022 Nov 15. Eur J Med Chem. 2023. PMID: 36459758 Free article.
2-aminobenzimidazoles for leishmaniasis: From initial hit discovery to in vivo profiling.
Ferreira RAA, Junior COR, Martinez PDG, Koovits PJ, Soares BM, Ferreira LLG, Michelan-Duarte S, Chelucci RC, Andricopulo AD, Galuppo MK, Uliana SRB, Matheeussen A, Caljon G, Maes L, Campbell S, Kratz JM, Mowbray CE, Dias LC. Ferreira RAA, et al. Among authors: martinez pdg. PLoS Negl Trop Dis. 2021 Feb 22;15(2):e0009196. doi: 10.1371/journal.pntd.0009196. eCollection 2021 Feb. PLoS Negl Trop Dis. 2021. PMID: 33617566 Free PMC article.
2,3,8-Trisubstituted Quinolines with Antimalarial Activity.
Martinez PDG, Krake SH, Poggi ML, Campbell SF, Willis PA, Dias LC. Martinez PDG, et al. An Acad Bras Cienc. 2018 May 21;90(1 Suppl 2):1215-1231. doi: 10.1590/0001-3765201820170820. Print 2018. An Acad Bras Cienc. 2018. PMID: 29791525 Free article.
Novel inhibitors of Plasmodium falciparum based on 2,5-disubstituted furans.
Krake SH, Martinez PDG, McLaren J, Ryan E, Chen G, White K, Charman SA, Campbell S, Willis P, Dias LC. Krake SH, et al. Among authors: martinez pdg. Eur J Med Chem. 2017 Jan 27;126:929-936. doi: 10.1016/j.ejmech.2016.12.024. Epub 2016 Dec 11. Eur J Med Chem. 2017. PMID: 28002775