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Imidazo[2,1-b]benzothiazol Derivatives as Potential Allosteric Inhibitors of the Glucocorticoid Receptor.
Christodoulou MS, Dapiaggi F, Ghiringhelli F, Pieraccini S, Sironi M, Lucafò M, Curci D, Decorti G, Stocco G, Chirumamilla CS, Vanden Berghe W, Balaguer P, Michel BY, Burger A, Beccalli EM, Passarella D, Martinet N. Christodoulou MS, et al. Among authors: martinet n. ACS Med Chem Lett. 2018 Feb 26;9(4):339-344. doi: 10.1021/acsmedchemlett.7b00527. eCollection 2018 Apr 12. ACS Med Chem Lett. 2018. PMID: 29670697 Free PMC article.
Quinazolinecarboline alkaloid evodiamine as scaffold for targeting topoisomerase I and sirtuins.
Christodoulou MS, Sacchetti A, Ronchetti V, Caufin S, Silvani A, Lesma G, Fontana G, Minicone F, Riva B, Ventura M, Lahtela-Kakkonen M, Jarho E, Zuco V, Zunino F, Martinet N, Dapiaggi F, Pieraccini S, Sironi M, Dalla Via L, Gia OM, Passarella D. Christodoulou MS, et al. Among authors: martinet n. Bioorg Med Chem. 2013 Nov 15;21(22):6920-8. doi: 10.1016/j.bmc.2013.09.030. Epub 2013 Sep 19. Bioorg Med Chem. 2013. PMID: 24103429
Boehmeriasin A as new lead compound for the inhibition of topoisomerases and SIRT2.
Christodoulou MS, Calogero F, Baumann M, García-Argáez AN, Pieraccini S, Sironi M, Dapiaggi F, Bucci R, Broggini G, Gazzola S, Liekens S, Silvani A, Lahtela-Kakkonen M, Martinet N, Nonell-Canals A, Santamaría-Navarro E, Baxendale IR, Dalla Via L, Passarella D. Christodoulou MS, et al. Among authors: martinet n. Eur J Med Chem. 2015 Mar 6;92:766-75. doi: 10.1016/j.ejmech.2015.01.038. Epub 2015 Jan 20. Eur J Med Chem. 2015. PMID: 25626146
Natural Products and Cancer Stem Cells.
Marucci C, Fumagalli G, Calogero F, Silvani A, Christodoulou MS, Martinet N, Passarella D. Marucci C, et al. Among authors: martinet n. Curr Pharm Des. 2015;21(38):5547-57. doi: 10.2174/1381612821666151002113114. Curr Pharm Des. 2015. PMID: 26429713 Review.
A High-throughput Screening of a Chemical Compound Library in Ovarian Cancer Stem Cells.
Ricci F, Carrassa L, Christodoulou MS, Passarella D, Michel B, Benhida R, Martinet N, Hunyadi A, Ioannou E, Roussis V, Musso L, Dallavalle S, Silvestri R, Westwood N, Mori M, Ingallina C, Botta B, Kavetsou E, Detsi A, Majer Z, Hudecz F, Bosze S, Kaminska B, Hansen TV, Bertrand P, Athanassopoulos CM, Damia G. Ricci F, et al. Among authors: martinet n. Comb Chem High Throughput Screen. 2018;21(1):50-56. doi: 10.2174/1386207321666180124093406. Comb Chem High Throughput Screen. 2018. PMID: 29366408
Aurones as histone deacetylase inhibitors: identification of key features.
Zwick V, Chatzivasileiou AO, Deschamps N, Roussaki M, Simões-Pires CA, Nurisso A, Denis I, Blanquart C, Martinet N, Carrupt PA, Detsi A, Cuendet M. Zwick V, et al. Among authors: martinet n. Bioorg Med Chem Lett. 2014 Dec 1;24(23):5497-501. doi: 10.1016/j.bmcl.2014.10.019. Epub 2014 Oct 13. Bioorg Med Chem Lett. 2014. PMID: 25455492
Cross metathesis with hydroxamate and benzamide BOC-protected alkenes to access HDAC inhibitors and their biological evaluation highlighted intrinsic activity of BOC-protected dihydroxamates.
Zwick V, Nurisso A, Simões-Pires C, Bouchet S, Martinet N, Lehotzky A, Ovadi J, Cuendet M, Blanquart C, Bertrand P. Zwick V, et al. Among authors: martinet n. Bioorg Med Chem Lett. 2016 Jan 1;26(1):154-9. doi: 10.1016/j.bmcl.2015.11.011. Epub 2015 Nov 11. Bioorg Med Chem Lett. 2016. PMID: 26611919
Synthesis of a selective HDAC6 inhibitor active in neuroblasts.
Zwick V, Simões-Pires CA, Nurisso A, Petit C, Dos Santos Passos C, Randazzo GM, Martinet N, Bertrand P, Cuendet M. Zwick V, et al. Among authors: martinet n. Bioorg Med Chem Lett. 2016 Oct 15;26(20):4955-4959. doi: 10.1016/j.bmcl.2016.09.011. Epub 2016 Sep 7. Bioorg Med Chem Lett. 2016. PMID: 27650925
131 results