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Humanized mice in studying efficacy and mechanisms of PD-1-targeted cancer immunotherapy.
Wang M, Yao LC, Cheng M, Cai D, Martinek J, Pan CX, Shi W, Ma AH, De Vere White RW, Airhart S, Liu ET, Banchereau J, Brehm MA, Greiner DL, Shultz LD, Palucka K, Keck JG. Wang M, et al. Among authors: martinek j. FASEB J. 2018 Mar;32(3):1537-1549. doi: 10.1096/fj.201700740R. Epub 2018 Jan 3. FASEB J. 2018. PMID: 29146734 Free PMC article.
Thus, tumor-bearing HuNSG mice may represent an important, new model for preclinical immunotherapy research.-Wang, M., Yao, L.-C., Cheng, M., Cai, D., Martinek, J., Pan, C.-X., Shi, W., Ma, A.-H., De Vere White, R. W., Airhart, S., Liu, E. T., Banchereau, J., …
Thus, tumor-bearing HuNSG mice may represent an important, new model for preclinical immunotherapy research.-Wang, M., Yao, L.-C., Cheng, M. …
Reprogramming tumor-infiltrating dendritic cells for CD103+ CD8+ mucosal T-cell differentiation and breast cancer rejection.
Wu TC, Xu K, Banchereau R, Marches F, Yu CI, Martinek J, Anguiano E, Pedroza-Gonzalez A, Snipes GJ, O'Shaughnessy J, Nishimura S, Liu YJ, Pascual V, Banchereau J, Oh S, Palucka K. Wu TC, et al. Among authors: martinek j. Cancer Immunol Res. 2014 May;2(5):487-500. doi: 10.1158/2326-6066.CIR-13-0217. Epub 2014 Mar 4. Cancer Immunol Res. 2014. PMID: 24795361 Free PMC article.
IL1 Receptor Antagonist Controls Transcriptional Signature of Inflammation in Patients with Metastatic Breast Cancer.
Wu TC, Xu K, Martinek J, Young RR, Banchereau R, George J, Turner J, Kim KI, Zurawski S, Wang X, Blankenship D, Brookes HM, Marches F, Obermoser G, Lavecchio E, Levin MK, Bae S, Chung CH, Smith JL, Cepika AM, Oxley KL, Snipes GJ, Banchereau J, Pascual V, O'Shaughnessy J, Palucka AK. Wu TC, et al. Among authors: martinek j. Cancer Res. 2018 Sep 15;78(18):5243-5258. doi: 10.1158/0008-5472.CAN-18-0413. Epub 2018 Jul 16. Cancer Res. 2018. PMID: 30012670 Free PMC article. Clinical Trial.
Interplay between dendritic cells and cancer cells.
Martinek J, Wu TC, Cadena D, Banchereau J, Palucka K. Martinek J, et al. Int Rev Cell Mol Biol. 2019;348:179-215. doi: 10.1016/bs.ircmb.2019.07.008. Epub 2019 Aug 30. Int Rev Cell Mol Biol. 2019. PMID: 31810553 Review.
Human KIT+ myeloid cells facilitate visceral metastasis by melanoma.
Yu CI, Martinek J, Wu TC, Kim KI, George J, Ahmadzadeh E, Maser R, Marches F, Metang P, Authie P, Oliveira VKP, Wang VG, Chuang JH, Robson P, Banchereau J, Palucka K. Yu CI, et al. Among authors: martinek j. J Exp Med. 2021 Jun 7;218(6):e20182163. doi: 10.1084/jem.20182163. J Exp Med. 2021. PMID: 33857287 Free PMC article.
Bronchial epithelium epithelial-mesenchymal plasticity forms aberrant basaloid-like cells in vitro.
Uthaya Kumar DB, Motakis E, Yurieva M, Kohar V, Martinek J, Wu TC, Khoury J, Grassmann J, Lu M, Palucka K, Kaminski N, Koff JL, Williams A. Uthaya Kumar DB, et al. Among authors: martinek j. Am J Physiol Lung Cell Mol Physiol. 2022 Jun 1;322(6):L822-L841. doi: 10.1152/ajplung.00254.2021. Epub 2022 Apr 19. Am J Physiol Lung Cell Mol Physiol. 2022. PMID: 35438006 Free PMC article.
Transcriptional profiling of macrophages in situ in metastatic melanoma reveals localization-dependent phenotypes and function.
Martinek J, Lin J, Kim KI, Wang VG, Wu TC, Chiorazzi M, Boruchov H, Gulati A, Seeniraj S, Sun L, Marches F, Robson P, Rongvaux A, Flavell RA, George J, Chuang JH, Banchereau J, Palucka K. Martinek J, et al. Cell Rep Med. 2022 May 17;3(5):100621. doi: 10.1016/j.xcrm.2022.100621. Epub 2022 Apr 27. Cell Rep Med. 2022. PMID: 35584631 Free PMC article.
Autologous humanized PDX modeling for immuno-oncology recapitulates features of the human tumor microenvironment.
Chiorazzi M, Martinek J, Krasnick B, Zheng Y, Robbins KJ, Qu R, Kaufmann G, Skidmore Z, Juric M, Henze LA, Brösecke F, Adonyi A, Zhao J, Shan L, Sefik E, Mudd J, Bi Y, Goedegebuure SP, Griffith M, Griffith O, Oyedeji A, Fertuzinhos S, Garcia-Milian R, Boffa D, Detterbeck F, Dhanasopon A, Blasberg J, Judson B, Gettinger S, Politi K, Kluger Y, Palucka K, Fields RC, Flavell RA. Chiorazzi M, et al. Among authors: martinek j. J Immunother Cancer. 2023 Jul;11(7):e006921. doi: 10.1136/jitc-2023-006921. J Immunother Cancer. 2023. PMID: 37487666 Free PMC article.
286 results