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Endogenous formaldehyde scavenges cellular glutathione resulting in redox disruption and cytotoxicity.
Umansky C, Morellato AE, Rieckher M, Scheidegger MA, Martinefski MR, Fernández GA, Pak O, Kolesnikova K, Reingruber H, Bollini M, Crossan GP, Sommer N, Monge ME, Schumacher B, Pontel LB. Umansky C, et al. Among authors: martinefski mr. Nat Commun. 2022 Feb 8;13(1):745. doi: 10.1038/s41467-022-28242-7. Nat Commun. 2022. PMID: 35136057 Free PMC article.
Synthesis and Antichlamydial Activity of Molecules Based on Dysregulators of Cylindrical Proteases.
Seleem MA, Rodrigues de Almeida N, Chhonker YS, Murry DJ, Guterres ZDR, Blocker AM, Kuwabara S, Fisher DJ, Leal ES, Martinefski MR, Bollini M, Monge ME, Ouellette SP, Conda-Sheridan M. Seleem MA, et al. Among authors: martinefski mr. J Med Chem. 2020 Apr 23;63(8):4370-4387. doi: 10.1021/acs.jmedchem.0c00371. Epub 2020 Apr 15. J Med Chem. 2020. PMID: 32227948 Free PMC article.
Correction to Synthesis and Antichlamydial Activity of Molecules Based on Dysregulators of Cylindrical Proteases.
Seleem MA, Rodrigues de Almeida N, Chhonker YS, Murry DJ, Guterres ZDR, Blocker AM, Kuwabara S, Fisher DJ, Leal ES, Martinefski MR, Bollini M, Monge ME, Ouellette SP, Conda-Sheridan M. Seleem MA, et al. Among authors: martinefski mr. J Med Chem. 2020 Oct 8;63(19):11302. doi: 10.1021/acs.jmedchem.0c01490. Epub 2020 Sep 18. J Med Chem. 2020. PMID: 32945169 No abstract available.
Urban air pollution induces redox imbalance and epithelium hyperplasia in mice cornea.
Lasagni Vitar RM, Hvozda Arana AG, Janezic NS, Marchini T, Tau J, Martinefski M, Tesone AI, Racca L, Reides CG, Tripodi V, Evelson PA, Berra A, Llesuy SF, Ferreira SM. Lasagni Vitar RM, et al. Toxicol Appl Pharmacol. 2019 Dec 1;384:114770. doi: 10.1016/j.taap.2019.114770. Epub 2019 Oct 16. Toxicol Appl Pharmacol. 2019. PMID: 31628919
NADPH oxidase and mitochondria are relevant sources of superoxide anion in the oxinflammatory response of macrophages exposed to airborne particulate matter.
Cáceres L, Paz ML, Garcés M, Calabró V, Magnani ND, Martinefski M, Martino Adami PV, Caltana L, Tasat D, Morelli L, Tripodi V, Valacchi G, Alvarez S, González Maglio D, Marchini T, Evelson P. Cáceres L, et al. Ecotoxicol Environ Saf. 2020 Dec 1;205:111186. doi: 10.1016/j.ecoenv.2020.111186. Epub 2020 Aug 24. Ecotoxicol Environ Saf. 2020. PMID: 32853868 Free article.
Fetal coenzyme Q10 deficiency in intrahepatic cholestasis of pregnancy.
Martinefski MR, Cocucci SE, Di Carlo MB, Vega HR, Lucangioli SE, Perazzi BE, Tripodi VP. Martinefski MR, et al. Clin Res Hepatol Gastroenterol. 2020 Jun;44(3):368-374. doi: 10.1016/j.clinre.2019.07.006. Epub 2019 Aug 30. Clin Res Hepatol Gastroenterol. 2020. PMID: 31477533
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