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STING agonism overcomes STAT3-mediated immunosuppression and adaptive resistance to PARP inhibition in ovarian cancer.
Ding L, Wang Q, Martincuks A, Kearns MJ, Jiang T, Lin Z, Cheng X, Qian C, Xie S, Kim HJ, Launonen IM, Färkkilä A, Roberts TM, Freeman GJ, Liu JF, Konstantinopoulos PA, Matulonis U, Yu H, Zhao JJ. Ding L, et al. Among authors: martincuks a. J Immunother Cancer. 2023 Jan;11(1):e005627. doi: 10.1136/jitc-2022-005627. J Immunother Cancer. 2023. PMID: 36609487 Free PMC article.
Niraparib-induced STAT3 inhibition increases its antitumor effects.
Zhao Q, Kohut A, Li YJ, Martincuks A, Austria T, Zhang C, Santiago NL, Borrero RM, Phan XT, Melstrom L, Rodriguez-Rodriguez L, Yu H. Zhao Q, et al. Among authors: martincuks a. Front Oncol. 2022 Oct 17;12:966492. doi: 10.3389/fonc.2022.966492. eCollection 2022. Front Oncol. 2022. PMID: 36324587 Free PMC article.
STAT proteins in cancer: orchestration of metabolism.
Li YJ, Zhang C, Martincuks A, Herrmann A, Yu H. Li YJ, et al. Among authors: martincuks a. Nat Rev Cancer. 2023 Mar;23(3):115-134. doi: 10.1038/s41568-022-00537-3. Epub 2023 Jan 3. Nat Rev Cancer. 2023. PMID: 36596870 Review.
Phase I trial of daily subcutaneous SPL-108 injections in combination with paclitaxel in patients with platinum resistant CD44+ advanced ovarian epithelial cancer.
Girda E, Hou J, Nelson D, Finlayson M, de Meritens AB, Chekmareiva M, Leiser A, Song M, Stephenson R, Chan N, Tergas AI, Vattakalam R, Wright JD, Yu H, Martincuks A, Kohut A, Palmer J, Rodriguez-Rodriguez L. Girda E, et al. Among authors: martincuks a. Int J Gynecol Cancer. 2022 Jun 24;32(8):1032-8. doi: 10.1136/ijgc-2021-003316. Online ahead of print. Int J Gynecol Cancer. 2022. PMID: 35750354 Free PMC article.
Corrigendum: Heparan Sulfate Induces Necroptosis in Murine Cardiomyocytes: A Medical-in-Silico Approach Combining In Vitro Experiments and Machine Learning.
Zechendorf E, Vaßen P, Zhang J, Hallawa A, Martincuks A, Krenkel O, Müller-Newen G, Schuerholz T, Simon TP, Marx G, Ascheid G, Schmeink A, Dartmann G, Thiemermann C, Martin L. Zechendorf E, et al. Among authors: martincuks a. Front Immunol. 2020 Dec 10;11:630463. doi: 10.3389/fimmu.2020.630463. eCollection 2020. Front Immunol. 2020. PMID: 33362805 Free PMC article.
Heparan Sulfate Induces Necroptosis in Murine Cardiomyocytes: A Medical-In silico Approach Combining In vitro Experiments and Machine Learning.
Zechendorf E, Vaßen P, Zhang J, Hallawa A, Martincuks A, Krenkel O, Müller-Newen G, Schuerholz T, Simon TP, Marx G, Ascheid G, Schmeink A, Dartmann G, Thiemermann C, Martin L. Zechendorf E, et al. Among authors: martincuks a. Front Immunol. 2018 Mar 20;9:393. doi: 10.3389/fimmu.2018.00393. eCollection 2018. Front Immunol. 2018. PMID: 29616016 Free PMC article.
15 results