Martin PL - Search Results

1

A Novel Bispecific Antibody Targeting EGFR and cMet Is Effective against EGFR Inhibitor-Resistant Lung Tumors.

Moores SL, Chiu ML, Bushey BS, Chevalier K, Luistro L, Dorn K, Brezski RJ, Haytko P, Kelly T, Wu SJ, Martin PL, Neijssen J, Parren PW, Schuurman J, Attar RM, Laquerre S, Lorenzi MV, Anderson GM. Moores SL, et al. Among authors: martin pl. Cancer Res. 2016 Jul 1;76(13):3942-53. doi: 10.1158/0008-5472.CAN-15-2833. Epub 2016 May 23. Cancer Res. 2016. PMID: 27216193

2

Absence of adverse effects in cynomolgus macaques treated with CNTO 95, a fully human anti-alphav integrin monoclonal antibody, despite widespread tissue binding.

Martin PL, Jiao Q, Cornacoff J, Hall W, Saville B, Nemeth JA, Schantz A, Mata M, Jang H, Fasanmade AA, Anderson L, Graham MA, Davis HM, Treacy G. Martin PL, et al. Clin Cancer Res. 2005 Oct 1;11(19 Pt 1):6959-65. doi: 10.1158/1078-0432.CCR-04-2623. Clin Cancer Res. 2005. PMID: 16203788

3

Safety Pharmacology of Anticancer Agents.

Martin PL. Martin PL. Handb Exp Pharmacol. 2015;229:405-31. doi: 10.1007/978-3-662-46943-9_16. Handb Exp Pharmacol. 2015. PMID: 26091649 Review.

4

Unexpected Toxicology Findings in Rats Dosed With an Antihuman IL-13 Monoclonal Antibody.

Martin PL, Nnane IP, Branigan P, Louden C. Martin PL, et al. Int J Toxicol. 2015 Sep-Oct;34(5):393-407. doi: 10.1177/1091581815591840. Epub 2015 Jun 29. Int J Toxicol. 2015. PMID: 26124191

5

Development in the cynomolgus macaque following administration of ustekinumab, a human anti-IL-12/23p40 monoclonal antibody, during pregnancy and lactation.

Martin PL, Sachs C, Imai N, Tsusaki H, Oneda S, Jiao Q, Treacy G. Martin PL, et al. Birth Defects Res B Dev Reprod Toxicol. 2010 Oct;89(5):351-63. doi: 10.1002/bdrb.20250. Birth Defects Res B Dev Reprod Toxicol. 2010. PMID: 20540088

6

Preclinical safety and pharmacology of an anti-human interleukin-13 monoclonal antibody in normal macaques and in macaques with allergic asthma.

Martin PL, Fisher D, Glass W, O'Neil K, Das A, Martin EC, Li L. Martin PL, et al. Among authors: martin ec. Int J Toxicol. 2008 Sep-Oct;27(5):351-8. doi: 10.1080/10915810802430509. Int J Toxicol. 2008. PMID: 19037805

7

Pharmacology and placental transfer of a human alphav integrin monoclonal antibody in rabbits.

Martin PL, Zhou Z, Van den Bulck K, Kwok D, Powers G, Jiao Q, Schantz A, Treacy G. Martin PL, et al. Birth Defects Res B Dev Reprod Toxicol. 2010 Apr;89(2):116-23. doi: 10.1002/bdrb.20232. Birth Defects Res B Dev Reprod Toxicol. 2010. PMID: 20151458

8

Development of a method for the evaluation of wound tensile strength in cynomolgus macaques.

Cornacoff JB, Howk K, Pikounis B, Mendenhall V, Martin P. Cornacoff JB, et al. J Pharmacol Toxicol Methods. 2008 Jan-Feb;57(1):74-9. doi: 10.1016/j.vascn.2007.08.002. Epub 2007 Sep 1. J Pharmacol Toxicol Methods. 2008. PMID: 17900932

9

Effects of CNTO 530, an erythropoietin mimetic-IgG4 fusion protein, on embryofetal development in rats and rabbits.

Martin PL, Sachs C, Hoberman A, Jiao Q, Bugelski PJ. Martin PL, et al. Birth Defects Res B Dev Reprod Toxicol. 2010 Apr;89(2):87-96. doi: 10.1002/bdrb.20227. Birth Defects Res B Dev Reprod Toxicol. 2010. PMID: 20077575

10

Considerations in assessing the developmental and reproductive toxicity potential of biopharmaceuticals.

Martin PL, Breslin W, Rocca M, Wright D, Cavagnaro J. Martin PL, et al. Birth Defects Res B Dev Reprod Toxicol. 2009 Jun;86(3):176-203. doi: 10.1002/bdrb.20197. Birth Defects Res B Dev Reprod Toxicol. 2009. PMID: 19462404 Review.

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