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Rare X-linked variants carry predominantly male risk in autism, Tourette syndrome, and ADHD.
Wang S, Wang B, Drury V, Drake S, Sun N, Alkhairo H, Arbelaez J, Duhn C; Tourette International Collaborative Genetics (TIC Genetics); Bal VH, Langley K, Martin J, Hoekstra PJ, Dietrich A, Xing J, Heiman GA, Tischfield JA, Fernandez TV, Owen MJ, O'Donovan MC, Thapar A, State MW, Willsey AJ. Wang S, et al. Among authors: martin j. Nat Commun. 2023 Dec 6;14(1):8077. doi: 10.1038/s41467-023-43776-0. Nat Commun. 2023. PMID: 38057346 Free PMC article.
Psychiatric gene discoveries shape evidence on ADHD's biology.
Thapar A, Martin J, Mick E, Arias Vásquez A, Langley K, Scherer SW, Schachar R, Crosbie J, Williams N, Franke B, Elia J, Glessner J, Hakonarson H, Owen MJ, Faraone SV, O'Donovan MC, Holmans P. Thapar A, et al. Among authors: martin j. Mol Psychiatry. 2016 Sep;21(9):1202-7. doi: 10.1038/mp.2015.163. Epub 2015 Nov 17. Mol Psychiatry. 2016. PMID: 26573769 Free PMC article.
Sex differences in anxiety and depression in children with attention deficit hyperactivity disorder: Investigating genetic liability and comorbidity.
Martin J, Shameem Agha S, Eyre O, Riglin L, Langley K, Hubbard L, Stergiakouli E; Psychiatric Genomics Consortium ADHD Working Group; O'Donovan M, Thapar A. Martin J, et al. Am J Med Genet B Neuropsychiatr Genet. 2021 Oct;186(7):412-422. doi: 10.1002/ajmg.b.32842. Epub 2021 May 3. Am J Med Genet B Neuropsychiatr Genet. 2021. PMID: 33939260
DRAGON-Data: a platform and protocol for integrating genomic and phenotypic data across large psychiatric cohorts.
Lynham AJ, Knott S, Underwood JFG, Hubbard L, Agha SS, Bisson JI, van den Bree MBM, Chawner SJRA, Craddock N, O'Donovan M, Jones IR, Kirov G, Langley K, Martin J, Rice F, Roberts NP, Thapar A, Anney R, Owen MJ, Hall J, Pardiñas AF, Walters JTR. Lynham AJ, et al. Among authors: martin j. BJPsych Open. 2023 Feb 8;9(2):e32. doi: 10.1192/bjo.2022.636. BJPsych Open. 2023. PMID: 36752340 Free PMC article.
Investigating the genetic underpinnings of early-life irritability.
Riglin L, Eyre O, Cooper M, Collishaw S, Martin J, Langley K, Leibenluft E, Stringaris A, Thapar AK, Maughan B, O'Donovan MC, Thapar A. Riglin L, et al. Among authors: martin j. Transl Psychiatry. 2017 Sep 26;7(9):e1241. doi: 10.1038/tp.2017.212. Transl Psychiatry. 2017. PMID: 28949337 Free PMC article.
Genome-wide analyses of ADHD identify 27 risk loci, refine the genetic architecture and implicate several cognitive domains.
Demontis D, Walters GB, Athanasiadis G, Walters R, Therrien K, Nielsen TT, Farajzadeh L, Voloudakis G, Bendl J, Zeng B, Zhang W, Grove J, Als TD, Duan J, Satterstrom FK, Bybjerg-Grauholm J, Bækved-Hansen M, Gudmundsson OO, Magnusson SH, Baldursson G, Davidsdottir K, Haraldsdottir GS, Agerbo E, Hoffman GE, Dalsgaard S, Martin J, Ribasés M, Boomsma DI, Soler Artigas M, Roth Mota N, Howrigan D, Medland SE, Zayats T, Rajagopal VM; ADHD Working Group of the Psychiatric Genomics Consortium; iPSYCH-Broad Consortium; Nordentoft M, Mors O, Hougaard DM, Mortensen PB, Daly MJ, Faraone SV, Stefansson H, Roussos P, Franke B, Werge T, Neale BM, Stefansson K, Børglum AD. Demontis D, et al. Among authors: martin j. Nat Genet. 2023 Feb;55(2):198-208. doi: 10.1038/s41588-022-01285-8. Epub 2023 Jan 26. Nat Genet. 2023. PMID: 36702997 Free PMC article.
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