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SMAD4 mutations and cross-talk between TGF-β/IFNγ signaling accelerate rates of DNA damage and cellular senescence, resulting in a segmental progeroid syndrome-the Myhre syndrome.
Kandhaya-Pillai R, Hou D, Zhang J, Yang X, Compoginis G, Mori T, Tchkonia T, Martin GM, Hisama FM, Kirkland JL, Oshima J. Kandhaya-Pillai R, et al. Among authors: martin gm. Geroscience. 2021 Jun;43(3):1481-1496. doi: 10.1007/s11357-020-00318-6. Epub 2021 Jan 5. Geroscience. 2021. PMID: 33428109 Free PMC article.
Ageing: Dietary protection for genes.
Oshima J, Martin GM. Oshima J, et al. Among authors: martin gm. Nature. 2016 Sep 15;537(7620):316-317. doi: 10.1038/nature19427. Epub 2016 Aug 24. Nature. 2016. PMID: 27556941 Free PMC article.
Lessons from human progeroid syndromes.
Martin GM, Oshima J. Martin GM, et al. Nature. 2000 Nov 9;408(6809):263-6. doi: 10.1038/35041705. Nature. 2000. PMID: 11089984 Review.
Accelerated epigenetic aging in Werner syndrome.
Maierhofer A, Flunkert J, Oshima J, Martin GM, Haaf T, Horvath S. Maierhofer A, et al. Among authors: martin gm. Aging (Albany NY). 2017 Apr;9(4):1143-1152. doi: 10.18632/aging.101217. Aging (Albany NY). 2017. PMID: 28377537 Free PMC article.
Epigenetic clock for skin and blood cells applied to Hutchinson Gilford Progeria Syndrome and ex vivo studies.
Horvath S, Oshima J, Martin GM, Lu AT, Quach A, Cohen H, Felton S, Matsuyama M, Lowe D, Kabacik S, Wilson JG, Reiner AP, Maierhofer A, Flunkert J, Aviv A, Hou L, Baccarelli AA, Li Y, Stewart JD, Whitsel EA, Ferrucci L, Matsuyama S, Raj K. Horvath S, et al. Among authors: martin gm. Aging (Albany NY). 2018 Jul 26;10(7):1758-1775. doi: 10.18632/aging.101508. Aging (Albany NY). 2018. PMID: 30048243 Free PMC article.
502 results