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The interaction of secreted phospholipase A2-IIA with the microbiota alters its lipidome and promotes inflammation.
Doré E, Joly-Beauparlant C, Morozumi S, Mathieu A, Lévesque T, Allaeys I, Duchez AC, Cloutier N, Leclercq M, Bodein A, Payré C, Martin C, Petit-Paitel A, Gelb MH, Rangachari M, Murakami M, Davidovic L, Flamand N, Arita M, Lambeau G, Droit A, Boilard E. Doré E, et al. Among authors: martin c. JCI Insight. 2022 Jan 25;7(2):e152638. doi: 10.1172/jci.insight.152638. JCI Insight. 2022. PMID: 35076027 Free PMC article.
Human leukocytes differentially express endocannabinoid-glycerol lipases and hydrolyze 2-arachidonoyl-glycerol and its metabolites from the 15-lipoxygenase and cyclooxygenase pathways.
Turcotte C, Dumais É, Archambault AS, Martin C, Blanchet MR, Bissonnette É, Boulet LP, Laviolette M, Di Marzo V, Flamand N. Turcotte C, et al. Among authors: martin c. J Leukoc Biol. 2019 Dec;106(6):1337-1347. doi: 10.1002/JLB.3A0919-049RRR. Epub 2019 Sep 26. J Leukoc Biol. 2019. PMID: 31556464
Alterations of brain endocannabinoidome signaling in germ-free mice.
Manca C, Shen M, Boubertakh B, Martin C, Flamand N, Silvestri C, Di Marzo V. Manca C, et al. Among authors: martin c. Biochim Biophys Acta Mol Cell Biol Lipids. 2020 Dec;1865(12):158786. doi: 10.1016/j.bbalip.2020.158786. Epub 2020 Aug 11. Biochim Biophys Acta Mol Cell Biol Lipids. 2020. PMID: 32795503
High levels of eicosanoids and docosanoids in the lungs of intubated COVID-19 patients.
Archambault AS, Zaid Y, Rakotoarivelo V, Turcotte C, Doré É, Dubuc I, Martin C, Flamand O, Amar Y, Cheikh A, Fares H, El Hassani A, Tijani Y, Côté A, Laviolette M, Boilard É, Flamand L, Flamand N. Archambault AS, et al. Among authors: martin c. FASEB J. 2021 Jun;35(6):e21666. doi: 10.1096/fj.202100540R. FASEB J. 2021. PMID: 34033145 Free PMC article. Clinical Trial.
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