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Multiple system atrophy and apolipoprotein E.
Ogaki K, Martens YA, Heckman MG, Koga S, Labbé C, Lorenzo-Betancor O, Wernick AI, Walton RL, Soto AI, Vargas ER, Nielsen HM, Fujioka S, Kanekiyo T, Uitti RJ, van Gerpen JA, Cheshire WP, Wszolek ZK, Low PA, Singer W, Dickson DW, Bu G, Ross OA. Ogaki K, et al. Among authors: martens ya. Mov Disord. 2018 Apr;33(4):647-650. doi: 10.1002/mds.27297. Epub 2018 Feb 14. Mov Disord. 2018. PMID: 29442376 Free PMC article.
Association study between multiple system atrophy and TREM2 p.R47H.
Ogaki K, Heckman MG, Koga S, Martens YA, Labbé C, Lorenzo-Betancor O, Walton RL, Soto AI, Vargas ER, Fujioka S, Uitti RJ, van Gerpen JA, Cheshire WP, Younkin SG, Wszolek ZK, Low PA, Singer W, Bu G, Dickson DW, Ross OA. Ogaki K, et al. Among authors: martens ya. Neurol Genet. 2018 Aug 1;4(4):e257. doi: 10.1212/NXG.0000000000000257. eCollection 2018 Aug. Neurol Genet. 2018. PMID: 30109269 Free PMC article.
APOE ε2 is associated with increased tau pathology in primary tauopathy.
Zhao N, Liu CC, Van Ingelgom AJ, Linares C, Kurti A, Knight JA, Heckman MG, Diehl NN, Shinohara M, Martens YA, Attrebi ON, Petrucelli L, Fryer JD, Wszolek ZK, Graff-Radford NR, Caselli RJ, Sanchez-Contreras MY, Rademakers R, Murray ME, Koga S, Dickson DW, Ross OA, Bu G. Zhao N, et al. Among authors: martens ya. Nat Commun. 2018 Oct 22;9(1):4388. doi: 10.1038/s41467-018-06783-0. Nat Commun. 2018. PMID: 30348994 Free PMC article.
APOE4-mediated amyloid-β pathology depends on its neuronal receptor LRP1.
Tachibana M, Holm ML, Liu CC, Shinohara M, Aikawa T, Oue H, Yamazaki Y, Martens YA, Murray ME, Sullivan PM, Weyer K, Glerup S, Dickson DW, Bu G, Kanekiyo T. Tachibana M, et al. Among authors: martens ya. J Clin Invest. 2019 Mar 1;129(3):1272-1277. doi: 10.1172/JCI124853. Epub 2019 Feb 11. J Clin Invest. 2019. PMID: 30741718 Free PMC article.
ABCA7 haplodeficiency disturbs microglial immune responses in the mouse brain.
Aikawa T, Ren Y, Yamazaki Y, Tachibana M, Johnson MR, Anderson CT, Martens YA, Holm ML, Asmann YW, Saito T, Saido TC, Fitzgerald ML, Bu G, Kanekiyo T. Aikawa T, et al. Among authors: martens ya. Proc Natl Acad Sci U S A. 2019 Nov 19;116(47):23790-23796. doi: 10.1073/pnas.1908529116. Epub 2019 Nov 5. Proc Natl Acad Sci U S A. 2019. PMID: 31690660 Free PMC article.
APOE4 exacerbates α-synuclein pathology and related toxicity independent of amyloid.
Zhao N, Attrebi ON, Ren Y, Qiao W, Sonustun B, Martens YA, Meneses AD, Li F, Shue F, Zheng J, Van Ingelgom AJ, Davis MD, Kurti A, Knight JA, Linares C, Chen Y, Delenclos M, Liu CC, Fryer JD, Asmann YW, McLean PJ, Dickson DW, Ross OA, Bu G. Zhao N, et al. Among authors: martens ya. Sci Transl Med. 2020 Feb 5;12(529):eaay1809. doi: 10.1126/scitranslmed.aay1809. Sci Transl Med. 2020. PMID: 32024798 Free PMC article.
44 results