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How I diagnose and treat NPM1-mutated AML.
Falini B, Brunetti L, Martelli MP. Falini B, et al. Among authors: martelli mp. Blood. 2021 Feb 4;137(5):589-599. doi: 10.1182/blood.2020008211. Blood. 2021. PMID: 33171486 Free article.
Anaplastic large cell lymphoma Hodgkin's-like: a randomized trial of ABVD versus MACOP-B with and without radiation therapy.
Zinzani PL, Martelli M, Magagnoli M, Zaccaria A, Ronconi F, Cantonetti M, Bocchia M, Marra R, Gobbi M, Falini B, Gherlinzoni F, Moretti L, De Renzo A, Mazza P, Pavone E, Sabattini E, Amendola A, Bendandi M, Pileri SA, Mandelli F, Tura S. Zinzani PL, et al. Blood. 1998 Aug 1;92(3):790-4. Blood. 1998. PMID: 9680346 Free article. Clinical Trial.
Both carboxy-terminus NES motif and mutated tryptophan(s) are crucial for aberrant nuclear export of nucleophosmin leukemic mutants in NPMc+ AML.
Falini B, Bolli N, Shan J, Martelli MP, Liso A, Pucciarini A, Bigerna B, Pasqualucci L, Mannucci R, Rosati R, Gorello P, Diverio D, Roti G, Tiacci E, Cazzaniga G, Biondi A, Schnittger S, Haferlach T, Hiddemann W, Martelli MF, Gu W, Mecucci C, Nicoletti I. Falini B, et al. Among authors: martelli mp, martelli mf. Blood. 2006 Jun 1;107(11):4514-23. doi: 10.1182/blood-2005-11-4745. Epub 2006 Feb 2. Blood. 2006. PMID: 16455950 Free article.
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