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Extracellular Superoxide Dismutase, the Endothelial Basement Membrane, and the WNT Pathway: New Players in Vascular Normalization and Tumor Infiltration by T-Cells.
Front Immunol. 2020 Oct 30;11:579552. doi: 10.3389/fimmu.2020.579552. eCollection 2020.
Front Immunol. 2020.
PMID: 33250894
Free PMC article.
Review.
SOD3 improves the tumor response to chemotherapy by stabilizing endothelial HIF-2α.
Mira E, Carmona-Rodríguez L, Pérez-Villamil B, Casas J, Fernández-Aceñero MJ, Martínez-Rey D, Martín-González P, Heras-Murillo I, Paz-Cabezas M, Tardáguila M, Oury TD, Martín-Puig S, Lacalle RA, Fabriás G, Díaz-Rubio E, Mañes S.
Mira E, et al. Among authors: martinez rey d.
Nat Commun. 2018 Feb 8;9(1):575. doi: 10.1038/s41467-018-03079-1.
Nat Commun. 2018.
PMID: 29422508
Free PMC article.
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SOD3 induces a HIF-2α-dependent program in endothelial cells that provides a selective signal for tumor infiltration by T cells.
Carmona-Rodríguez L, Martínez-Rey D, Fernández-Aceñero MJ, González-Martín A, Paz-Cabezas M, Rodríguez-Rodríguez N, Pérez-Villamil B, Sáez ME, Díaz-Rubio E, Mira E, Mañes S.
Carmona-Rodríguez L, et al. Among authors: martinez rey d.
J Immunother Cancer. 2020 Jun;8(1):e000432. doi: 10.1136/jitc-2019-000432.
J Immunother Cancer. 2020.
PMID: 32591431
Free PMC article.
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SOD3 boosts T cell infiltration by normalizing the tumor endothelium and inducing laminin-α4.
Carmona-Rodríguez L, Martínez-Rey D, Mira E, Mañes S.
Carmona-Rodríguez L, et al. Among authors: martinez rey d.
Oncoimmunology. 2020 Jul 12;9(1):1794163. doi: 10.1080/2162402X.2020.1794163.
Oncoimmunology. 2020.
PMID: 32934887
Free PMC article.
Review.
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Superoxide Dismutase-3 Downregulates Laminin α5 Expression in Tumor Endothelial Cells via the Inhibition of Nuclear Factor Kappa B Signaling.
Carmona-Rodríguez L, Martínez-Rey D, Martín-González P, Franch M, Sorokin L, Mira E, Mañes S.
Carmona-Rodríguez L, et al. Among authors: martinez rey d.
Cancers (Basel). 2022 Feb 26;14(5):1226. doi: 10.3390/cancers14051226.
Cancers (Basel). 2022.
PMID: 35267534
Free PMC article.
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