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Effect of Sugar 2',4'-Modifications on Gene Silencing Activity of siRNA Duplexes.
Malek-Adamian E, Fakhoury J, Arnold AE, Martínez-Montero S, Shoichet MS, Damha MJ. Malek-Adamian E, et al. Among authors: martinez montero s. Nucleic Acid Ther. 2019 Aug;29(4):187-194. doi: 10.1089/nat.2019.0792. Epub 2019 May 14. Nucleic Acid Ther. 2019. PMID: 31084536 Free PMC article.
4'-C-Methoxy-2'-deoxy-2'-fluoro Modified Ribonucleotides Improve Metabolic Stability and Elicit Efficient RNAi-Mediated Gene Silencing.
Malek-Adamian E, Guenther DC, Matsuda S, Martínez-Montero S, Zlatev I, Harp J, Burai Patrascu M, Foster DJ, Fakhoury J, Perkins L, Moitessier N, Manoharan RM, Taneja N, Bisbe A, Charisse K, Maier M, Rajeev KG, Egli M, Manoharan M, Damha MJ. Malek-Adamian E, et al. Among authors: martinez montero s. J Am Chem Soc. 2017 Oct 18;139(41):14542-14555. doi: 10.1021/jacs.7b07582. Epub 2017 Oct 6. J Am Chem Soc. 2017. PMID: 28937776
Structure of human IFIT1 with capped RNA reveals adaptable mRNA binding and mechanisms for sensing N1 and N2 ribose 2'-O methylations.
Abbas YM, Laudenbach BT, Martínez-Montero S, Cencic R, Habjan M, Pichlmair A, Damha MJ, Pelletier J, Nagar B. Abbas YM, et al. Among authors: martinez montero s. Proc Natl Acad Sci U S A. 2017 Mar 14;114(11):E2106-E2115. doi: 10.1073/pnas.1612444114. Epub 2017 Mar 1. Proc Natl Acad Sci U S A. 2017. PMID: 28251928 Free PMC article.
Nucleotide Sugar Pucker Preference Mitigates Excision by HIV-1 RT.
Yamada K, Wahba AS, Bernatchez JA, Ilina T, Martínez-Montero S, Habibian M, Deleavey GF, Götte M, Parniak MA, Damha MJ. Yamada K, et al. Among authors: martinez montero s. ACS Chem Biol. 2015 Sep 18;10(9):2024-33. doi: 10.1021/acschembio.5b00263. Epub 2015 Jul 22. ACS Chem Biol. 2015. PMID: 26131619 Free PMC article.
16 results