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In vitro development of imipenem/relebactam resistance in KPC-producing Klebsiella pneumoniae involves multiple mutations including OmpK36 disruption and KPC modification.
Gato E, Guijarro-Sánchez P, Alonso-García I, Pedraza-Merino R, Conde A, Lence E, Rumbo-Feal S, Peña-Escolano A, Lasarte-Monterrubio C, Blanco-Martín T, Fernández-González A, Fernández-López MDC, Maceiras R, Martínez-Guitián M, Vázquez-Ucha JC, Martínez-Martínez L, González-Bello C, Arca-Suárez J, Beceiro A, Bou G. Gato E, et al. Among authors: martinez guitian m. Int J Antimicrob Agents. 2023 Oct;62(4):106935. doi: 10.1016/j.ijantimicag.2023.106935. Epub 2023 Aug 3. Int J Antimicrob Agents. 2023. PMID: 37541530
Challenging Antimicrobial Susceptibility and Evolution of Resistance (OXA-681) during Treatment of a Long-Term Nosocomial Infection Caused by a Pseudomonas aeruginosa ST175 Clone.
Arca-Suárez J, Fraile-Ribot P, Vázquez-Ucha JC, Cabot G, Martínez-Guitián M, Lence E, González-Bello C, Beceiro A, Rodríguez-Iglesias M, Galán-Sánchez F, Bou G, Oliver A. Arca-Suárez J, et al. Antimicrob Agents Chemother. 2019 Sep 23;63(10):e01110-19. doi: 10.1128/AAC.01110-19. Print 2019 Oct. Antimicrob Agents Chemother. 2019. PMID: 31383659 Free PMC article.
Therapeutic Efficacy of LN-1-255 in Combination with Imipenem in Severe Infection Caused by Carbapenem-Resistant Acinetobacter baumannii.
Vázquez-Ucha JC, Martínez-Guitián M, Maneiro M, Conde-Pérez K, Álvarez-Fraga L, Torrens G, Oliver A, Buynak JD, Bonomo RA, Bou G, González-Bello C, Poza M, Beceiro A. Vázquez-Ucha JC, et al. Antimicrob Agents Chemother. 2019 Sep 23;63(10):e01092-19. doi: 10.1128/AAC.01092-19. Print 2019 Oct. Antimicrob Agents Chemother. 2019. PMID: 31383666 Free PMC article.
Activity of aztreonam in combination with novel β-lactamase inhibitors against metallo-β-lactamase-producing Enterobacterales from Spain.
Vázquez-Ucha JC, Alonso-Garcia I, Guijarro-Sánchez P, Lasarte-Monterrubio C, Álvarez-Fraga L, Cendón-Esteve A, Outeda M, Maceiras R, Peña-Escolano A, Martínez-Guitián M, Arca-Suárez J, Bou G, Beceiro A; GEMARA-SEIMC/REIPI Enterobacterales Study Group. Vázquez-Ucha JC, et al. Among authors: martinez guitian m. Int J Antimicrob Agents. 2023 Apr;61(4):106738. doi: 10.1016/j.ijantimicag.2023.106738. Epub 2023 Feb 3. Int J Antimicrob Agents. 2023. PMID: 36736925
Simultaneous and divergent evolution of resistance to cephalosporin/β-lactamase inhibitor combinations and imipenem/relebactam following ceftazidime/avibactam treatment of MDR Pseudomonas aeruginosa infections.
Alonso-García I, Vázquez-Ucha JC, Lasarte-Monterrubio C, González-Mayo E, Lada-Salvador P, Vela-Fernández R, Aja-Macaya P, Guijarro-Sánchez P, Rumbo-Feal S, Muíño-Andrade M, Fernández-González A, Martínez-Guitián M, Beceiro A, Rodríguez-Iglesias M, Oliver A, Arca-Suárez J, Galán-Sánchez F, Bou G. Alonso-García I, et al. Among authors: martinez guitian m. J Antimicrob Chemother. 2023 May 3;78(5):1195-1200. doi: 10.1093/jac/dkad062. J Antimicrob Chemother. 2023. PMID: 36918743
Antimicrobial Activity of Cefiderocol against the Carbapenemase-Producing Enterobacter cloacae Complex and Characterization of Reduced Susceptibility Associated with Metallo-β-Lactamase VIM-1.
Lasarte-Monterrubio C, Guijarro-Sánchez P, Vázquez-Ucha JC, Alonso-Garcia I, Alvarez-Fraga L, Outeda M, Martinez-Guitian M, Peña-Escolano A, Maceiras R, Lence E, González-Bello C, Arca-Suárez J, Bou G, Beceiro A. Lasarte-Monterrubio C, et al. Among authors: martinez guitian m. Antimicrob Agents Chemother. 2023 May 17;67(5):e0150522. doi: 10.1128/aac.01505-22. Epub 2023 Apr 13. Antimicrob Agents Chemother. 2023. PMID: 37195077 Free PMC article.
29 results