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Silencing hepatic MCJ attenuates non-alcoholic fatty liver disease (NAFLD) by increasing mitochondrial fatty acid oxidation.
Barbier-Torres L, Fortner KA, Iruzubieta P, Delgado TC, Giddings E, Chen Y, Champagne D, Fernández-Ramos D, Mestre D, Gomez-Santos B, Varela-Rey M, de Juan VG, Fernández-Tussy P, Zubiete-Franco I, García-Monzón C, González-Rodríguez Á, Oza D, Valença-Pereira F, Fang Q, Crespo J, Aspichueta P, Tremblay F, Christensen BC, Anguita J, Martínez-Chantar ML, Rincón M. Barbier-Torres L, et al. Nat Commun. 2020 Jul 3;11(1):3360. doi: 10.1038/s41467-020-16991-2. Nat Commun. 2020. PMID: 32620763 Free PMC article.
Alcohol, DNA methylation, and cancer.
Varela-Rey M, Woodhoo A, Martinez-Chantar ML, Mato JM, Lu SC. Varela-Rey M, et al. Alcohol Res. 2013;35(1):25-35. Alcohol Res. 2013. PMID: 24313162 Free PMC article. Review.
SIRT1 controls liver regeneration by regulating bile acid metabolism through farnesoid X receptor and mammalian target of rapamycin signaling.
García-Rodríguez JL, Barbier-Torres L, Fernández-Álvarez S, Gutiérrez-de Juan V, Monte MJ, Halilbasic E, Herranz D, Álvarez L, Aspichueta P, Marín JJ, Trauner M, Mato JM, Serrano M, Beraza N, Martínez-Chantar ML. García-Rodríguez JL, et al. Hepatology. 2014 May;59(5):1972-83. doi: 10.1002/hep.26971. Epub 2014 Mar 31. Hepatology. 2014. PMID: 24338587 Free PMC article.
Regulation of oxidative stress by methylation-controlled J protein controls macrophage responses to inflammatory insults.
Navasa N, Martín I, Iglesias-Pedraz JM, Beraza N, Atondo E, Izadi H, Ayaz F, Fernández-Álvarez S, Hatle K, Som A, Dienz O, Osborne BA, Martínez-Chantar ML, Rincón M, Anguita J. Navasa N, et al. J Infect Dis. 2015 Jan 1;211(1):135-45. doi: 10.1093/infdis/jiu389. Epub 2014 Jul 14. J Infect Dis. 2015. PMID: 25028693 Free PMC article.
Histone deacetylase 4 promotes cholestatic liver injury in the absence of prohibitin-1.
Barbier-Torres L, Beraza N, Fernández-Tussy P, Lopitz-Otsoa F, Fernández-Ramos D, Zubiete-Franco I, Varela-Rey M, Delgado TC, Gutiérrez V, Anguita J, Pares A, Banales JM, Villa E, Caballería J, Alvarez L, Lu SC, Mato JM, Martínez-Chantar ML. Barbier-Torres L, et al. Hepatology. 2015 Oct;62(4):1237-48. doi: 10.1002/hep.27959. Epub 2015 Jul 31. Hepatology. 2015. PMID: 26109312 Free PMC article.
Methionine and S-adenosylmethionine levels are critical regulators of PP2A activity modulating lipophagy during steatosis.
Zubiete-Franco I, García-Rodríguez JL, Martínez-Uña M, Martínez-Lopez N, Woodhoo A, Juan VG, Beraza N, Lage-Medina S, Andrade F, Fernandez ML, Aldámiz-Echevarría L, Fernández-Ramos D, Falcon-Perez JM, Lopitz-Otsoa F, Fernandez-Tussy P, Barbier-Torres L, Luka Z, Wagner C, García-Monzón C, Lu SC, Aspichueta P, Mato JM, Martínez-Chantar ML, Varela-Rey M. Zubiete-Franco I, et al. J Hepatol. 2016 Feb;64(2):409-418. doi: 10.1016/j.jhep.2015.08.037. Epub 2015 Sep 21. J Hepatol. 2016. PMID: 26394163 Free PMC article.
Stratification and therapeutic potential of PML in metastatic breast cancer.
Martín-Martín N, Piva M, Urosevic J, Aldaz P, Sutherland JD, Fernández-Ruiz S, Arreal L, Torrano V, Cortazar AR, Planet E, Guiu M, Radosevic-Robin N, Garcia S, Macías I, Salvador F, Domenici G, Rueda OM, Zabala-Letona A, Arruabarrena-Aristorena A, Zúñiga-García P, Caro-Maldonado A, Valcárcel-Jiménez L, Sánchez-Mosquera P, Varela-Rey M, Martínez-Chantar ML, Anguita J, Ibrahim YH, Scaltriti M, Lawrie CH, Aransay AM, Iovanna JL, Baselga J, Caldas C, Barrio R, Serra V, Vivanco Md, Matheu A, Gomis RR, Carracedo A. Martín-Martín N, et al. Nat Commun. 2016 Aug 24;7:12595. doi: 10.1038/ncomms12595. Nat Commun. 2016. PMID: 27553708 Free PMC article.
An update on the use of benzoate, phenylacetate and phenylbutyrate ammonia scavengers for interrogating and modifying liver nitrogen metabolism and its implications in urea cycle disorders and liver disease.
De Las Heras J, Aldámiz-Echevarría L, Martínez-Chantar ML, Delgado TC. De Las Heras J, et al. Expert Opin Drug Metab Toxicol. 2017 Apr;13(4):439-448. doi: 10.1080/17425255.2017.1262843. Epub 2016 Nov 28. Expert Opin Drug Metab Toxicol. 2017. PMID: 27860485 Free PMC article. Review.
Metabolomic Identification of Subtypes of Nonalcoholic Steatohepatitis.
Alonso C, Fernández-Ramos D, Varela-Rey M, Martínez-Arranz I, Navasa N, Van Liempd SM, Lavín Trueba JL, Mayo R, Ilisso CP, de Juan VG, Iruarrizaga-Lejarreta M, delaCruz-Villar L, Mincholé I, Robinson A, Crespo J, Martín-Duce A, Romero-Gómez M, Sann H, Platon J, Van Eyk J, Aspichueta P, Noureddin M, Falcón-Pérez JM, Anguita J, Aransay AM, Martínez-Chantar ML, Lu SC, Mato JM. Alonso C, et al. Gastroenterology. 2017 May;152(6):1449-1461.e7. doi: 10.1053/j.gastro.2017.01.015. Epub 2017 Jan 26. Gastroenterology. 2017. PMID: 28132890 Free PMC article.
213 results