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Targeting Hepatic Glutaminase 1 Ameliorates Non-alcoholic Steatohepatitis by Restoring Very-Low-Density Lipoprotein Triglyceride Assembly.
Simon J, Nuñez-García M, Fernández-Tussy P, Barbier-Torres L, Fernández-Ramos D, Gómez-Santos B, Buqué X, Lopitz-Otsoa F, Goikoetxea-Usandizaga N, Serrano-Macia M, Rodriguez-Agudo R, Bizkarguenaga M, Zubiete-Franco I, Gutiérrez-de Juan V, Cabrera D, Alonso C, Iruzubieta P, Romero-Gomez M, van Liempd S, Castro A, Nogueiras R, Varela-Rey M, Falcón-Pérez JM, Villa E, Crespo J, Lu SC, Mato JM, Aspichueta P, Delgado TC, Martínez-Chantar ML. Simon J, et al. Cell Metab. 2020 Mar 3;31(3):605-622.e10. doi: 10.1016/j.cmet.2020.01.013. Epub 2020 Feb 21. Cell Metab. 2020. PMID: 32084378 Free PMC article.
Purification, crystallization and preliminary X-ray diffraction analysis of the CBS-domain pair from the Methanococcus jannaschii protein MJ0100.
Lucas M, Kortazar D, Astigarraga E, Fernández JA, Mato JM, Martínez-Chantar ML, Martínez-Cruz LA. Lucas M, et al. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2008 Oct 1;64(Pt 10):936-41. doi: 10.1107/S1744309108027930. Epub 2008 Sep 30. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2008. PMID: 18931440 Free PMC article.
Purification, crystallization and preliminary crystallographic analysis of protein MJ1225 from Methanocaldococcus jannaschii, a putative archaeal homologue of gamma-AMPK.
Gómez García I, Kortázar D, Oyenarte I, Mato JM, Martínez-Chantar ML, Martínez-Cruz LA. Gómez García I, et al. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2009 Aug 1;65(Pt 8):813-7. doi: 10.1107/S1744309109026475. Epub 2009 Jul 30. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2009. PMID: 19652347 Free PMC article.
Mitochondrial GSH determines the toxic or therapeutic potential of superoxide scavenging in steatohepatitis.
von Montfort C, Matias N, Fernandez A, Fucho R, Conde de la Rosa L, Martinez-Chantar ML, Mato JM, Machida K, Tsukamoto H, Murphy MP, Mansouri A, Kaplowitz N, Garcia-Ruiz C, Fernandez-Checa JC. von Montfort C, et al. J Hepatol. 2012 Oct;57(4):852-9. doi: 10.1016/j.jhep.2012.05.024. Epub 2012 Jun 9. J Hepatol. 2012. PMID: 22687340 Free PMC article.
A DNA methylation signature associated with the epigenetic repression of glycine N-methyltransferase in human hepatocellular carcinoma.
Huidobro C, Toraño EG, Fernández AF, Urdinguio RG, Rodríguez RM, Ferrero C, Martínez-Camblor P, Boix L, Bruix J, García-Rodríguez JL, Varela-Rey M, Mato JM, Martínez-Chantar ML, Fraga MF. Huidobro C, et al. J Mol Med (Berl). 2013 Aug;91(8):939-50. doi: 10.1007/s00109-013-1010-8. Epub 2013 Mar 12. J Mol Med (Berl). 2013. PMID: 23475283
Alcohol, DNA methylation, and cancer.
Varela-Rey M, Woodhoo A, Martinez-Chantar ML, Mato JM, Lu SC. Varela-Rey M, et al. Alcohol Res. 2013;35(1):25-35. Alcohol Res. 2013. PMID: 24313162 Free PMC article. Review.
SIRT1 controls liver regeneration by regulating bile acid metabolism through farnesoid X receptor and mammalian target of rapamycin signaling.
García-Rodríguez JL, Barbier-Torres L, Fernández-Álvarez S, Gutiérrez-de Juan V, Monte MJ, Halilbasic E, Herranz D, Álvarez L, Aspichueta P, Marín JJ, Trauner M, Mato JM, Serrano M, Beraza N, Martínez-Chantar ML. García-Rodríguez JL, et al. Hepatology. 2014 May;59(5):1972-83. doi: 10.1002/hep.26971. Epub 2014 Mar 31. Hepatology. 2014. PMID: 24338587 Free PMC article.
213 results