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Targeted microbubbles carrying lipid-oil-nanodroplets for ultrasound-triggered delivery of the hydrophobic drug, combretastatin A4.
Charalambous A, Mico V, McVeigh LE, Marston G, Ingram N, Volpato M, Peyman SA, McLaughlan JR, Wierzbicki A, Loadman PM, Bushby RJ, Markham AF, Evans SD, Coletta PL. Charalambous A, et al. Among authors: marston g. Nanomedicine. 2021 Aug;36:102401. doi: 10.1016/j.nano.2021.102401. Epub 2021 Apr 22. Nanomedicine. 2021. PMID: 33894396 Free article.
Ultrasound-triggered therapeutic microbubbles enhance the efficacy of cytotoxic drugs by increasing circulation and tumor drug accumulation and limiting bioavailability and toxicity in normal tissues.
Ingram N, McVeigh LE, Abou-Saleh RH, Maynard J, Peyman SA, McLaughlan JR, Fairclough M, Marston G, Valleley EMA, Jimenez-Macias JL, Charalambous A, Townley W, Haddrick M, Wierzbicki A, Wright A, Volpato M, Simpson PB, Treanor DE, Thomson NH, Loadman PM, Bushby RJ, Johnson BRG, Jones PF, Evans JA, Freear S, Markham AF, Evans SD, Coletta PL. Ingram N, et al. Among authors: marston g. Theranostics. 2020 Sep 1;10(24):10973-10992. doi: 10.7150/thno.49670. eCollection 2020. Theranostics. 2020. PMID: 33042265 Free PMC article.
The omega-3 polyunsaturated fatty acid eicosapentaenoic acid inhibits mouse MC-26 colorectal cancer cell liver metastasis via inhibition of PGE2-dependent cell motility.
Hawcroft G, Volpato M, Marston G, Ingram N, Perry SL, Cockbain AJ, Race AD, Munarini A, Belluzzi A, Loadman PM, Coletta PL, Hull MA. Hawcroft G, et al. Among authors: marston g. Br J Pharmacol. 2012 Jul;166(5):1724-37. doi: 10.1111/j.1476-5381.2012.01882.x. Br J Pharmacol. 2012. PMID: 22300262 Free PMC article.
Changes in plasma chemokine C-C motif ligand 2 levels during treatment with eicosapentaenoic acid predict outcome in patients undergoing surgery for colorectal cancer liver metastasis.
Volpato M, Perry SL, Marston G, Ingram N, Cockbain AJ, Burghel H, Mann J, Lowes D, Wilson E, Droop A, Randerson-Moor J, Coletta PL, Hull MA. Volpato M, et al. Among authors: marston g. Oncotarget. 2016 May 10;7(19):28139-50. doi: 10.18632/oncotarget.8579. Oncotarget. 2016. PMID: 27058904 Free PMC article. Clinical Trial.
50 results