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Population Pharmacokinetics of the Novel Adenosine A2A Antagonist/Inverse Agonist KW-6356 and Its Active Metabolite Following Single and Multiple Oral Administration in Healthy Individuals and Patients with Parkinson's Disease.
Tayama T, Okada H, Ogawa K, Marsteller D, Maeda H, Hruska MW, Kagawa Y. Tayama T, et al. Among authors: marsteller d. Clin Pharmacol Drug Dev. 2024 May;13(5):549-559. doi: 10.1002/cpdd.1359. Epub 2024 Jan 4. Clin Pharmacol Drug Dev. 2024. PMID: 38178727
Sigma-1 and dopamine D2/D3 receptor occupancy of pridopidine in healthy volunteers and patients with Huntington disease: a [18F] fluspidine and [18F] fallypride PET study.
Grachev ID, Meyer PM, Becker GA, Bronzel M, Marsteller D, Pastino G, Voges O, Rabinovich L, Knebel H, Zientek F, Rullmann M, Sattler B, Patt M, Gerhards T, Strauss M, Kluge A, Brust P, Savola JM, Gordon MF, Geva M, Hesse S, Barthel H, Hayden MR, Sabri O. Grachev ID, et al. Among authors: marsteller d. Eur J Nucl Med Mol Imaging. 2021 Apr;48(4):1103-1115. doi: 10.1007/s00259-020-05030-3. Epub 2020 Sep 29. Eur J Nucl Med Mol Imaging. 2021. PMID: 32995944 Free PMC article.
Effect of fixed-dose subcutaneous reslizumab on asthma exacerbations in patients with severe uncontrolled asthma and corticosteroid sparing in patients with oral corticosteroid-dependent asthma: results from two phase 3, randomised, double-blind, placebo-controlled trials.
Bernstein JA, Virchow JC, Murphy K, Maspero JF, Jacobs J, Adir Y, Humbert M, Castro M, Marsteller DA, McElhattan J, Hickey L, Garin M, Vanlandingham R, Brusselle G. Bernstein JA, et al. Among authors: marsteller da. Lancet Respir Med. 2020 May;8(5):461-474. doi: 10.1016/S2213-2600(19)30372-8. Epub 2020 Feb 14. Lancet Respir Med. 2020. PMID: 32066536 Clinical Trial.
The novel neuropeptide Y Y5 receptor antagonist Lu AA33810 [N-[[trans-4-[(4,5-dihydro[1]benzothiepino[5,4-d]thiazol-2-yl)amino]cyclohexyl]methyl]-methanesulfonamide] exerts anxiolytic- and antidepressant-like effects in rat models of stress sensitivity.
Walker MW, Wolinsky TD, Jubian V, Chandrasena G, Zhong H, Huang X, Miller S, Hegde LG, Marsteller DA, Marzabadi MR, Papp M, Overstreet DH, Gerald CP, Craig DA. Walker MW, et al. Among authors: marsteller da. J Pharmacol Exp Ther. 2009 Mar;328(3):900-11. doi: 10.1124/jpet.108.144634. Epub 2008 Dec 19. J Pharmacol Exp Ther. 2009. PMID: 19098165
Rapamycin-conditioned, alloantigen-pulsed dendritic cells promote indefinite survival of vascularized skin allografts in association with T regulatory cell expansion.
Horibe EK, Sacks J, Unadkat J, Raimondi G, Wang Z, Ikeguchi R, Marsteller D, Ferreira LM, Thomson AW, Lee WP, Feili-Hariri M. Horibe EK, et al. Among authors: marsteller d. Transpl Immunol. 2008 Feb;18(4):307-18. doi: 10.1016/j.trim.2007.10.007. Epub 2007 Nov 5. Transpl Immunol. 2008. PMID: 18158116
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