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The Medium-Chain Fatty Acid Receptor GPR84 Mediates Myeloid Cell Infiltration Promoting Steatohepatitis and Fibrosis.
Puengel T, De Vos S, Hundertmark J, Kohlhepp M, Guldiken N, Pujuguet P, Auberval M, Marsais F, Shoji KF, Saniere L, Trautwein C, Luedde T, Strnad P, Brys R, Clément-Lacroix P, Tacke F. Puengel T, et al. Among authors: marsais f. J Clin Med. 2020 Apr 16;9(4):1140. doi: 10.3390/jcm9041140. J Clin Med. 2020. PMID: 32316235 Free PMC article.
Neutralization of IL-17C Reduces Skin Inflammation in Mouse Models of Psoriasis and Atopic Dermatitis.
Vandeghinste N, Klattig J, Jagerschmidt C, Lavazais S, Marsais F, Haas JD, Auberval M, Lauffer F, Moran T, Ongenaert M, Van Balen M, Dupont S, Lepescheux L, Garcia T, Härtle S, Eyerich K, Fallon PG, Brys R, Steidl S. Vandeghinste N, et al. Among authors: marsais f. J Invest Dermatol. 2018 Jul;138(7):1555-1563. doi: 10.1016/j.jid.2018.01.036. Epub 2018 Feb 21. J Invest Dermatol. 2018. PMID: 29474945 Free article.
Discovery and Optimization of Orally Bioavailable Phthalazone and Cinnolone Carboxylic Acid Derivatives as S1P2 Antagonists against Fibrotic Diseases.
Mammoliti O, Jansen K, El Bkassiny S, Palisse A, Triballeau N, Bucher D, Allart B, Jaunet A, Tricarico G, De Wachter M, Menet C, Blanc J, Letfus V, Rupčić R, Šmehil M, Poljak T, Coornaert B, Sonck K, Duys I, Waeckel L, Lecru L, Marsais F, Jagerschmidt C, Auberval M, Pujuguet P, Oste L, Borgonovi M, Wakselman E, Christophe T, Houvenaghel N, Jans M, Heckmann B, Sanière L, Brys R. Mammoliti O, et al. Among authors: marsais f. J Med Chem. 2021 Oct 14;64(19):14557-14586. doi: 10.1021/acs.jmedchem.1c01066. Epub 2021 Sep 28. J Med Chem. 2021. PMID: 34581584
IRAK4 inhibition dampens pathogenic processes driving inflammatory skin diseases.
Lavazais S, Jargosch M, Dupont S, Labéguère F, Menet C, Jagerschmidt C, Ohm F, Kupcsik L, Parent I, Cottereaux C, Marsais F, Oste L, Van de Water A, Christophe T, De Vos S, Fallon P, Lauffer F, Clément-Lacroix P, Eyerich K, Brys R. Lavazais S, et al. Among authors: marsais f. Sci Transl Med. 2023 Feb 15;15(683):eabj3289. doi: 10.1126/scitranslmed.abj3289. Epub 2023 Feb 15. Sci Transl Med. 2023. PMID: 36791209
IL-17C amplifies epithelial inflammation in human psoriasis and atopic eczema.
Lauffer F, Jargosch M, Baghin V, Krause L, Kempf W, Absmaier-Kijak M, Morelli M, Madonna S, Marsais F, Lepescheux L, Albanesi C, Müller NS, Theis FJ, Schmidt-Weber C, Eyerich S, Biedermann T, Vandeghinste N, Steidl S, Eyerich K. Lauffer F, et al. Among authors: marsais f. J Eur Acad Dermatol Venereol. 2020 Apr;34(4):800-809. doi: 10.1111/jdv.16126. Epub 2020 Jan 19. J Eur Acad Dermatol Venereol. 2020. PMID: 31793105
Autotaxin facilitates selective LPA receptor signaling.
Salgado-Polo F, Borza R, Matsoukas MT, Marsais F, Jagerschmidt C, Waeckel L, Moolenaar WH, Ford P, Heckmann B, Perrakis A. Salgado-Polo F, et al. Among authors: marsais f. Cell Chem Biol. 2023 Jan 19;30(1):69-84.e14. doi: 10.1016/j.chembiol.2022.12.006. Epub 2023 Jan 13. Cell Chem Biol. 2023. PMID: 36640760 Free article.
Synthesis of the heterocyclic core of the D-series GE2270.
Berini C, Martin T, Lassalas P, Marsais F, Baudequin C, Hoarau C. Berini C, et al. Among authors: marsais f. Beilstein J Org Chem. 2017 Jul 17;13:1407-1412. doi: 10.3762/bjoc.13.137. eCollection 2017. Beilstein J Org Chem. 2017. PMID: 28781706 Free PMC article.
Dihydroquinoline Carbamate Derivatives as "Bio-oxidizable" Prodrugs for Brain Delivery of Acetylcholinesterase Inhibitors: [¹¹C] Radiosynthesis and Biological Evaluation.
Bohn P, Gourand F, Papamicaël C, Ibazizène M, Dhilly M, Gembus V, Alix F, Ţînţaş ML, Marsais F, Barré L, Levacher V. Bohn P, et al. Among authors: marsais f. ACS Chem Neurosci. 2015 May 20;6(5):737-44. doi: 10.1021/cn5003539. Epub 2015 Feb 27. ACS Chem Neurosci. 2015. PMID: 25695305
46 results