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Novel activity-based probes for broad-spectrum profiling of retaining β-exoglucosidases in situ and in vivo.
Kallemeijn WW, Li KY, Witte MD, Marques AR, Aten J, Scheij S, Jiang J, Willems LI, Voorn-Brouwer TM, van Roomen CP, Ottenhoff R, Boot RG, van den Elst H, Walvoort MT, Florea BI, Codée JD, van der Marel GA, Aerts JM, Overkleeft HS. Kallemeijn WW, et al. Among authors: marques ar. Angew Chem Int Ed Engl. 2012 Dec 7;51(50):12529-33. doi: 10.1002/anie.201207771. Epub 2012 Nov 8. Angew Chem Int Ed Engl. 2012. PMID: 23139194
Reducing GBA2 Activity Ameliorates Neuropathology in Niemann-Pick Type C Mice.
Marques AR, Aten J, Ottenhoff R, van Roomen CP, Herrera Moro D, Claessen N, Vinueza Veloz MF, Zhou K, Lin Z, Mirzaian M, Boot RG, De Zeeuw CI, Overkleeft HS, Yildiz Y, Aerts JM. Marques AR, et al. PLoS One. 2015 Aug 14;10(8):e0135889. doi: 10.1371/journal.pone.0135889. eCollection 2015. PLoS One. 2015. PMID: 26275242 Free PMC article.
Visualization of Active Glucocerebrosidase in Rodent Brain with High Spatial Resolution following In Situ Labeling with Fluorescent Activity Based Probes.
Herrera Moro Chao D, Kallemeijn WW, Marques AR, Orre M, Ottenhoff R, van Roomen C, Foppen E, Renner MC, Moeton M, van Eijk M, Boot RG, Kamphuis W, Hol EM, Aten J, Overkleeft HS, Kalsbeek A, Aerts JM. Herrera Moro Chao D, et al. Among authors: marques ar. PLoS One. 2015 Sep 29;10(9):e0138107. doi: 10.1371/journal.pone.0138107. eCollection 2015. PLoS One. 2015. PMID: 26418157 Free PMC article.
Glucosylated cholesterol in mammalian cells and tissues: formation and degradation by multiple cellular β-glucosidases.
Marques AR, Mirzaian M, Akiyama H, Wisse P, Ferraz MJ, Gaspar P, Ghauharali-van der Vlugt K, Meijer R, Giraldo P, Alfonso P, Irún P, Dahl M, Karlsson S, Pavlova EV, Cox TM, Scheij S, Verhoek M, Ottenhoff R, van Roomen CP, Pannu NS, van Eijk M, Dekker N, Boot RG, Overkleeft HS, Blommaart E, Hirabayashi Y, Aerts JM. Marques AR, et al. J Lipid Res. 2016 Mar;57(3):451-63. doi: 10.1194/jlr.M064923. Epub 2016 Jan 2. J Lipid Res. 2016. PMID: 26724485 Free PMC article.
Accurate quantification of sphingosine-1-phosphate in normal and Fabry disease plasma, cells and tissues by LC-MS/MS with (13)C-encoded natural S1P as internal standard.
Mirzaian M, Wisse P, Ferraz MJ, Marques ARA, Gabriel TL, van Roomen CPAA, Ottenhoff R, van Eijk M, Codée JDC, van der Marel GA, Overkleeft HS, Aerts JM. Mirzaian M, et al. Clin Chim Acta. 2016 Aug 1;459:36-44. doi: 10.1016/j.cca.2016.05.017. Epub 2016 May 21. Clin Chim Acta. 2016. PMID: 27221202
177 results