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A novel potent class I HDAC inhibitor reverses the STAT4/p66Shc apoptotic defect in B cells from chronic lymphocytic leukemia patients.
Rossi S, Tatangelo V, Dichiara M, Butini S, Gemma S, Brogi S, Pasquini S, Cappello M, Vincenzi F, Varani K, Lopresti L, Malchiodi M, Carrara C, Gozzetti A, Bocchia M, Marotta G, Patrussi L, Carullo G, Baldari CT, Campiani G. Rossi S, et al. Among authors: marotta g. Biomed Pharmacother. 2024 May;174:116537. doi: 10.1016/j.biopha.2024.116537. Epub 2024 Apr 4. Biomed Pharmacother. 2024. PMID: 38579402 Free article.
p66Shc deficiency in CLL cells enhances PD-L1 expression and suppresses immune synapse formation.
Lopresti L, Capitani N, Tatangelo V, Tangredi C, Boncompagni G, Frezzato F, Visentin A, Marotta G, Ciofini S, Gozzetti A, Bocchia M, Trentin L, Baldari CT, Patrussi L. Lopresti L, et al. Among authors: marotta g. Front Cell Dev Biol. 2024 Jan 23;12:1297116. doi: 10.3389/fcell.2024.1297116. eCollection 2024. Front Cell Dev Biol. 2024. PMID: 38389706 Free PMC article.
Leukemic cell-secreted interleukin-9 suppresses cytotoxic T cell-mediated killing in chronic lymphocytic leukemia.
Boncompagni G, Tatangelo V, Lopresti L, Ulivieri C, Capitani N, Tangredi C, Finetti F, Marotta G, Frezzato F, Visentin A, Ciofini S, Gozzetti A, Bocchia M, Calzada-Fraile D, Martin Cofreces NB, Trentin L, Patrussi L, Baldari CT. Boncompagni G, et al. Among authors: marotta g. Cell Death Dis. 2024 Feb 15;15(2):144. doi: 10.1038/s41419-024-06528-6. Cell Death Dis. 2024. PMID: 38360867 Free PMC article.
Human colorectal cancer: upregulation of the adaptor protein Rai in TILs leads to cell dysfunction by sustaining GSK-3 activation and PD-1 expression.
Montecchi T, Nannini G, De Tommaso D, Cassioli C, Coppola F, Ringressi MN, Carraro F, Naldini A, Taddei A, Marotta G, Amedei A, Baldari CT, Ulivieri C. Montecchi T, et al. Among authors: marotta g. Cancer Immunol Immunother. 2024 Jan 4;73(1):2. doi: 10.1007/s00262-023-03614-0. Cancer Immunol Immunother. 2024. PMID: 38175205 Free PMC article.
265 results