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The interferon landscape along the respiratory tract impacts the severity of COVID-19.
Sposito B, Broggi A, Pandolfi L, Crotta S, Clementi N, Ferrarese R, Sisti S, Criscuolo E, Spreafico R, Long JM, Ambrosi A, Liu E, Frangipane V, Saracino L, Bozzini S, Marongiu L, Facchini FA, Bottazzi A, Fossali T, Colombo R, Clementi M, Tagliabue E, Chou J, Pontiroli AE, Meloni F, Wack A, Mancini N, Zanoni I. Sposito B, et al. Among authors: marongiu l. Cell. 2021 Sep 16;184(19):4953-4968.e16. doi: 10.1016/j.cell.2021.08.016. Epub 2021 Aug 19. Cell. 2021. PMID: 34492226 Free PMC article.
Below the surface: The inner lives of TLR4 and TLR9.
Marongiu L, Gornati L, Artuso I, Zanoni I, Granucci F. Marongiu L, et al. J Leukoc Biol. 2019 Jul;106(1):147-160. doi: 10.1002/JLB.3MIR1218-483RR. Epub 2019 Mar 22. J Leukoc Biol. 2019. PMID: 30900780 Free PMC article. Review.
Maturation signatures of conventional dendritic cell subtypes in COVID-19 suggest direct viral sensing.
Marongiu L, Protti G, Facchini FA, Valache M, Mingozzi F, Ranzani V, Putignano AR, Salviati L, Bevilacqua V, Curti S, Crosti M, Sarnicola ML, D'Angiò M, Bettini LR, Biondi A, Nespoli L, Tamini N, Clementi N, Mancini N, Abrignani S, Spreafico R, Granucci F. Marongiu L, et al. Eur J Immunol. 2022 Jan;52(1):109-122. doi: 10.1002/eji.202149298. Epub 2021 Oct 1. Eur J Immunol. 2022. PMID: 34333764 Free PMC article.
An adjuvant strategy enabled by modulation of the physical properties of microbial ligands expands antigen immunogenicity.
Borriello F, Poli V, Shrock E, Spreafico R, Liu X, Pishesha N, Carpenet C, Chou J, Di Gioia M, McGrath ME, Dillen CA, Barrett NA, Lacanfora L, Franco ME, Marongiu L, Iwakura Y, Pucci F, Kruppa MD, Ma Z, Lowman DW, Ensley HE, Nanishi E, Saito Y, O'Meara TR, Seo HS, Dhe-Paganon S, Dowling DJ, Frieman M, Elledge SJ, Levy O, Irvine DJ, Ploegh HL, Williams DL, Zanoni I. Borriello F, et al. Among authors: marongiu l. Cell. 2022 Feb 17;185(4):614-629.e21. doi: 10.1016/j.cell.2022.01.009. Epub 2022 Feb 10. Cell. 2022. PMID: 35148840 Free PMC article.
Specific immunosuppressive role of nanodrugs targeting calcineurin in innate myeloid cells.
Colombo M, Marongiu L, Mingozzi F, Marzi R, Cigni C, Facchini FA, Rotem R, Valache M, Stucchi G, Rocca G, Gornati L, Rizzuto MA, Salvioni L, Zanoni I, Gori A, Prosperi D, Granucci F. Colombo M, et al. Among authors: marongiu l. iScience. 2022 Aug 30;25(10):105042. doi: 10.1016/j.isci.2022.105042. eCollection 2022 Oct 21. iScience. 2022. PMID: 36124235 Free PMC article.
Inositol 1,4,5-trisphosphate 3-kinase B promotes Ca2+ mobilization and the inflammatory activity of dendritic cells.
Marongiu L, Mingozzi F, Cigni C, Marzi R, Di Gioia M, Garrè M, Parazzoli D, Sironi L, Collini M, Sakaguchi R, Morii T, Crosti M, Moro M, Schurmans S, Catelani T, Rotem R, Colombo M, Shears S, Prosperi D, Zanoni I, Granucci F. Marongiu L, et al. Sci Signal. 2021 Mar 30;14(676):eaaz2120. doi: 10.1126/scisignal.aaz2120. Sci Signal. 2021. PMID: 33785611 Free PMC article.
68 results