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Page 1
A Smo/Gli Multitarget Hedgehog Pathway Inhibitor Impairs Tumor Growth.
Lospinoso Severini L, Quaglio D, Basili I, Ghirga F, Bufalieri F, Caimano M, Balducci S, Moretti M, Romeo I, Loricchio E, Maroder M, Botta B, Mori M, Infante P, Di Marcotullio L. Lospinoso Severini L, et al. Among authors: maroder m. Cancers (Basel). 2019 Oct 9;11(10):1518. doi: 10.3390/cancers11101518. Cancers (Basel). 2019. PMID: 31601026 Free PMC article.
REN(KCTD11) is a suppressor of Hedgehog signaling and is deleted in human medulloblastoma.
Di Marcotullio L, Ferretti E, De Smaele E, Argenti B, Mincione C, Zazzeroni F, Gallo R, Masuelli L, Napolitano M, Maroder M, Modesti A, Giangaspero F, Screpanti I, Alesse E, Gulino A. Di Marcotullio L, et al. Among authors: maroder m. Proc Natl Acad Sci U S A. 2004 Jul 20;101(29):10833-8. doi: 10.1073/pnas.0400690101. Epub 2004 Jul 12. Proc Natl Acad Sci U S A. 2004. PMID: 15249678 Free PMC article.
Alternative splicing of the ErbB-4 cytoplasmic domain and its regulation by hedgehog signaling identify distinct medulloblastoma subsets.
Ferretti E, Di Marcotullio L, Gessi M, Mattei T, Greco A, Po A, De Smaele E, Giangaspero F, Riccardi R, Di Rocco C, Pazzaglia S, Maroder M, Alimandi M, Screpanti I, Gulino A. Ferretti E, et al. Among authors: maroder m. Oncogene. 2006 Nov 23;25(55):7267-73. doi: 10.1038/sj.onc.1209716. Epub 2006 Jul 31. Oncogene. 2006. PMID: 16878160
An integrated approach identifies Nhlh1 and Insm1 as Sonic Hedgehog-regulated genes in developing cerebellum and medulloblastoma.
De Smaele E, Fragomeli C, Ferretti E, Pelloni M, Po A, Canettieri G, Coni S, Di Marcotullio L, Greco A, Moretti M, Di Rocco C, Pazzaglia S, Maroder M, Screpanti I, Giannini G, Gulino A. De Smaele E, et al. Among authors: maroder m. Neoplasia. 2008 Jan;10(1):89-98. doi: 10.1593/neo.07891. Neoplasia. 2008. PMID: 18231642 Free PMC article.
Identification and characterization of KCASH2 and KCASH3, 2 novel Cullin3 adaptors suppressing histone deacetylase and Hedgehog activity in medulloblastoma.
De Smaele E, Di Marcotullio L, Moretti M, Pelloni M, Occhione MA, Infante P, Cucchi D, Greco A, Pietrosanti L, Todorovic J, Coni S, Canettieri G, Ferretti E, Bei R, Maroder M, Screpanti I, Gulino A. De Smaele E, et al. Among authors: maroder m. Neoplasia. 2011 Apr;13(4):374-85. doi: 10.1593/neo.101630. Neoplasia. 2011. PMID: 21472142 Free PMC article.
Itch/β-arrestin2-dependent non-proteolytic ubiquitylation of SuFu controls Hedgehog signalling and medulloblastoma tumorigenesis.
Infante P, Faedda R, Bernardi F, Bufalieri F, Lospinoso Severini L, Alfonsi R, Mazzà D, Siler M, Coni S, Po A, Petroni M, Ferretti E, Mori M, De Smaele E, Canettieri G, Capalbo C, Maroder M, Screpanti I, Kool M, Pfister SM, Guardavaccaro D, Gulino A, Di Marcotullio L. Infante P, et al. Among authors: maroder m. Nat Commun. 2018 Mar 7;9(1):976. doi: 10.1038/s41467-018-03339-0. Nat Commun. 2018. PMID: 29515120 Free PMC article.
Mitogen-activated kinase kinase kinase 1 inhibits hedgehog signaling and medulloblastoma growth through GLI1 phosphorylation.
Antonucci L, Di Magno L, D'Amico D, Manni S, Serrao SM, Di Pastena F, Bordone R, Yurtsever ZN, Caimano M, Petroni M, Giorgi A, Schininà ME, Yates Iii JR, Di Marcotullio L, De Smaele E, Checquolo S, Capalbo C, Agostinelli E, Maroder M, Coni S, Canettieri G. Antonucci L, et al. Among authors: maroder m. Int J Oncol. 2019 Feb;54(2):505-514. doi: 10.3892/ijo.2018.4638. Epub 2018 Nov 19. Int J Oncol. 2019. PMID: 30483764 Free PMC article.
KCTD15 inhibits the Hedgehog pathway in Medulloblastoma cells by increasing protein levels of the oncosuppressor KCASH2.
Spiombi E, Angrisani A, Fonte S, De Feudis G, Fabretti F, Cucchi D, Izzo M, Infante P, Miele E, Po A, Di Magno L, Magliozzi R, Guardavaccaro D, Maroder M, Canettieri G, Giannini G, Ferretti E, Gulino A, Di Marcotullio L, Moretti M, De Smaele E. Spiombi E, et al. Among authors: maroder m. Oncogenesis. 2019 Nov 4;8(11):64. doi: 10.1038/s41389-019-0175-6. Oncogenesis. 2019. PMID: 31685809 Free PMC article.
53 results