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Essential fatty acids deficiency promotes lipogenic gene expression and hepatic steatosis through the liver X receptor.
Ducheix S, Montagner A, Polizzi A, Lasserre F, Marmugi A, Bertrand-Michel J, Podechard N, Al Saati T, Chétiveaux M, Baron S, Boué J, Dietrich G, Mselli-Lakhal L, Costet P, Lobaccaro JM, Pineau T, Theodorou V, Postic C, Martin PG, Guillou H. Ducheix S, et al. J Hepatol. 2013 May;58(5):984-92. doi: 10.1016/j.jhep.2013.01.006. Epub 2013 Jan 16. J Hepatol. 2013. PMID: 23333450
Activation of the Constitutive Androstane Receptor induces hepatic lipogenesis and regulates Pnpla3 gene expression in a LXR-independent way.
Marmugi A, Lukowicz C, Lasserre F, Montagner A, Polizzi A, Ducheix S, Goron A, Gamet-Payrastre L, Gerbal-Chaloin S, Pascussi JM, Moldes M, Pineau T, Guillou H, Mselli-Lakhal L. Marmugi A, et al. Toxicol Appl Pharmacol. 2016 Jul 15;303:90-100. doi: 10.1016/j.taap.2016.05.006. Epub 2016 May 11. Toxicol Appl Pharmacol. 2016. PMID: 27180240
Are BPA Substitutes as Obesogenic as BPA?
Oliviero F, Marmugi A, Viguié C, Gayrard V, Picard-Hagen N, Mselli-Lakhal L. Oliviero F, et al. Int J Mol Sci. 2022 Apr 11;23(8):4238. doi: 10.3390/ijms23084238. Int J Mol Sci. 2022. PMID: 35457054 Free PMC article. Review.
Sorcin Links Pancreatic β-Cell Lipotoxicity to ER Ca2+ Stores.
Marmugi A, Parnis J, Chen X, Carmichael L, Hardy J, Mannan N, Marchetti P, Piemonti L, Bosco D, Johnson P, Shapiro JA, Cruciani-Guglielmacci C, Magnan C, Ibberson M, Thorens B, Valdivia HH, Rutter GA, Leclerc I. Marmugi A, et al. Diabetes. 2016 Apr;65(4):1009-21. doi: 10.2337/db15-1334. Epub 2016 Jan 28. Diabetes. 2016. PMID: 26822088 Free PMC article.