Marmorstein R - Search Results

1

Development of small-molecule inhibitors of the group I p21-activated kinases, emerging therapeutic targets in cancer.

Yi C, Maksimoska J, Marmorstein R, Kissil JL. Yi C, et al. Among authors: marmorstein r. Biochem Pharmacol. 2010 Sep 1;80(5):683-9. doi: 10.1016/j.bcp.2010.03.012. Epub 2010 Mar 17. Biochem Pharmacol. 2010. PMID: 20302846 Free PMC article. Review.

2

Identification of BRAF inhibitors through in silico screening.

Luo C, Xie P, Marmorstein R. Luo C, et al. Among authors: marmorstein r. J Med Chem. 2008 Oct 9;51(19):6121-6127. doi: 10.1021/jm800539g. Epub 2008 Sep 11. J Med Chem. 2008. PMID: 18783202 Free PMC article.

3

Targeting large kinase active site with rigid, bulky octahedral ruthenium complexes.

Maksimoska J, Feng L, Harms K, Yi C, Kissil J, Marmorstein R, Meggers E. Maksimoska J, et al. Among authors: marmorstein r. J Am Chem Soc. 2008 Nov 26;130(47):15764-5. doi: 10.1021/ja805555a. J Am Chem Soc. 2008. PMID: 18973295 Free PMC article.

4

Toward the development of a potent and selective organoruthenium mammalian sterile 20 kinase inhibitor.

Anand R, Maksimoska J, Pagano N, Wong EY, Gimotty PA, Diamond SL, Meggers E, Marmorstein R. Anand R, et al. Among authors: marmorstein r. J Med Chem. 2009 Mar 26;52(6):1602-11. doi: 10.1021/jm8005806. J Med Chem. 2009. PMID: 19226137 Free PMC article.

5

Structurally sophisticated octahedral metal complexes as highly selective protein kinase inhibitors.

Feng L, Geisselbrecht Y, Blanck S, Wilbuer A, Atilla-Gokcumen GE, Filippakopoulos P, Kräling K, Celik MA, Harms K, Maksimoska J, Marmorstein R, Frenking G, Knapp S, Essen LO, Meggers E. Feng L, et al. Among authors: marmorstein r. J Am Chem Soc. 2011 Apr 20;133(15):5976-86. doi: 10.1021/ja1112996. Epub 2011 Mar 29. J Am Chem Soc. 2011. PMID: 21446733 Free PMC article.

6

A tight junction-associated Merlin-angiomotin complex mediates Merlin's regulation of mitogenic signaling and tumor suppressive functions.

Yi C, Troutman S, Fera D, Stemmer-Rachamimov A, Avila JL, Christian N, Persson NL, Shimono A, Speicher DW, Marmorstein R, Holmgren L, Kissil JL. Yi C, et al. Among authors: marmorstein r. Cancer Cell. 2011 Apr 12;19(4):527-40. doi: 10.1016/j.ccr.2011.02.017. Cancer Cell. 2011. PMID: 21481793 Free PMC article.

7

The art of filling protein pockets efficiently with octahedral metal complexes.

Blanck S, Maksimoska J, Baumeister J, Harms K, Marmorstein R, Meggers E. Blanck S, et al. Among authors: marmorstein r. Angew Chem Int Ed Engl. 2012 May 21;51(21):5244-6. doi: 10.1002/anie.201108865. Epub 2012 Mar 1. Angew Chem Int Ed Engl. 2012. PMID: 22383326 Free PMC article. No abstract available.

8

Identification and characterization of small molecule antagonists of pRb inactivation by viral oncoproteins.

Fera D, Schultz DC, Hodawadekar S, Reichman M, Donover PS, Melvin J, Troutman S, Kissil JL, Huryn DM, Marmorstein R. Fera D, et al. Among authors: marmorstein r. Chem Biol. 2012 Apr 20;19(4):518-28. doi: 10.1016/j.chembiol.2012.03.007. Chem Biol. 2012. PMID: 22520758 Free PMC article.

9

FRAX597, a small molecule inhibitor of the p21-activated kinases, inhibits tumorigenesis of neurofibromatosis type 2 (NF2)-associated Schwannomas.

Licciulli S, Maksimoska J, Zhou C, Troutman S, Kota S, Liu Q, Duron S, Campbell D, Chernoff J, Field J, Marmorstein R, Kissil JL. Licciulli S, et al. Among authors: marmorstein r. J Biol Chem. 2013 Oct 4;288(40):29105-14. doi: 10.1074/jbc.M113.510933. Epub 2013 Aug 19. J Biol Chem. 2013. PMID: 23960073 Free PMC article.

10

Structure of the p300 histone acetyltransferase bound to acetyl-coenzyme A and its analogues.

Maksimoska J, Segura-Peña D, Cole PA, Marmorstein R. Maksimoska J, et al. Among authors: marmorstein r. Biochemistry. 2014 Jun 3;53(21):3415-22. doi: 10.1021/bi500380f. Epub 2014 May 21. Biochemistry. 2014. PMID: 24819397 Free PMC article.

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