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Targeted microbubbles carrying lipid-oil-nanodroplets for ultrasound-triggered delivery of the hydrophobic drug, combretastatin A4.
Charalambous A, Mico V, McVeigh LE, Marston G, Ingram N, Volpato M, Peyman SA, McLaughlan JR, Wierzbicki A, Loadman PM, Bushby RJ, Markham AF, Evans SD, Coletta PL. Charalambous A, et al. Among authors: markham af. Nanomedicine. 2021 Aug;36:102401. doi: 10.1016/j.nano.2021.102401. Epub 2021 Apr 22. Nanomedicine. 2021. PMID: 33894396 Free article.
Ultrasound-triggered therapeutic microbubbles enhance the efficacy of cytotoxic drugs by increasing circulation and tumor drug accumulation and limiting bioavailability and toxicity in normal tissues.
Ingram N, McVeigh LE, Abou-Saleh RH, Maynard J, Peyman SA, McLaughlan JR, Fairclough M, Marston G, Valleley EMA, Jimenez-Macias JL, Charalambous A, Townley W, Haddrick M, Wierzbicki A, Wright A, Volpato M, Simpson PB, Treanor DE, Thomson NH, Loadman PM, Bushby RJ, Johnson BRG, Jones PF, Evans JA, Freear S, Markham AF, Evans SD, Coletta PL. Ingram N, et al. Among authors: markham af. Theranostics. 2020 Sep 1;10(24):10973-10992. doi: 10.7150/thno.49670. eCollection 2020. Theranostics. 2020. PMID: 33042265 Free PMC article.
Freeze-Dried Therapeutic Microbubbles: Stability and Gas Exchange.
Abou-Saleh RH, Delaney A, Ingram N, Batchelor DVB, Johnson BRG, Charalambous A, Bushby RJ, Peyman SA, Coletta PL, Markham AF, Evans SD. Abou-Saleh RH, et al. Among authors: markham af. ACS Appl Bio Mater. 2020 Nov 16;3(11):7840-7848. doi: 10.1021/acsabm.0c00982. Epub 2020 Oct 30. ACS Appl Bio Mater. 2020. PMID: 35019524 Free article.
317 results