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Tracing the origins of relapse in acute myeloid leukaemia to stem cells.
Nature. 2017 Jul 6;547(7661):104-108. doi: 10.1038/nature22993. Epub 2017 Jun 28.
Nature. 2017.
PMID: 28658204
Identification of pre-leukaemic haematopoietic stem cells in acute leukaemia.
Shlush LI, Zandi S, Mitchell A, Chen WC, Brandwein JM, Gupta V, Kennedy JA, Schimmer AD, Schuh AC, Yee KW, McLeod JL, Doedens M, Medeiros JJ, Marke R, Kim HJ, Lee K, McPherson JD, Hudson TJ; HALT Pan-Leukemia Gene Panel Consortium; Brown AM, Yousif F, Trinh QM, Stein LD, Minden MD, Wang JC, Dick JE.
Shlush LI, et al. Among authors: marke r.
Nature. 2014 Feb 20;506(7488):328-33. doi: 10.1038/nature13038. Epub 2014 Feb 12.
Nature. 2014.
PMID: 24522528
Free PMC article.
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miR-126 Regulates Distinct Self-Renewal Outcomes in Normal and Malignant Hematopoietic Stem Cells.
Lechman ER, Gentner B, Ng SW, Schoof EM, van Galen P, Kennedy JA, Nucera S, Ciceri F, Kaufmann KB, Takayama N, Dobson SM, Trotman-Grant A, Krivdova G, Elzinga J, Mitchell A, Nilsson B, Hermans KG, Eppert K, Marke R, Isserlin R, Voisin V, Bader GD, Zandstra PW, Golub TR, Ebert BL, Lu J, Minden M, Wang JC, Naldini L, Dick JE.
Lechman ER, et al. Among authors: marke r.
Cancer Cell. 2016 Feb 8;29(2):214-28. doi: 10.1016/j.ccell.2015.12.011. Epub 2016 Jan 28.
Cancer Cell. 2016.
PMID: 26832662
Free PMC article.
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miR-126 Regulates Distinct Self-Renewal Outcomes in Normal and Malignant Hematopoietic Stem Cells.
Lechman ER, Gentner B, Ng SWK, Schoof EM, van Galen P, Kennedy JA, Nucera S, Ciceri F, Kaufmann KB, Takayama N, Dobson SM, Trotman-Grant A, Krivdova G, Elzinga J, Mitchell A, Nilsson B, Hermans KG, Eppert K, Marke R, Isserlin R, Voisin V, Bader GD, Zandstra PW, Golub TR, Ebert BL, Lu J, Minden M, Wang JCY, Naldini L, Dick JE.
Lechman ER, et al. Among authors: marke r.
Cancer Cell. 2016 Apr 11;29(4):602-606. doi: 10.1016/j.ccell.2016.03.015.
Cancer Cell. 2016.
PMID: 27070706
Free PMC article.
No abstract available.
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Tumor suppressors BTG1 and IKZF1 cooperate during mouse leukemia development and increase relapse risk in B-cell precursor acute lymphoblastic leukemia patients.
Scheijen B, Boer JM, Marke R, Tijchon E, van Ingen Schenau D, Waanders E, van Emst L, van der Meer LT, Pieters R, Escherich G, Horstmann MA, Sonneveld E, Venn N, Sutton R, Dalla-Pozza L, Kuiper RP, Hoogerbrugge PM, den Boer ML, van Leeuwen FN.
Scheijen B, et al. Among authors: marke r.
Haematologica. 2017 Mar;102(3):541-551. doi: 10.3324/haematol.2016.153023. Epub 2016 Dec 15.
Haematologica. 2017.
PMID: 27979924
Free PMC article.
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The many faces of IKZF1 in B-cell precursor acute lymphoblastic leukemia.
Marke R, van Leeuwen FN, Scheijen B.
Marke R, et al.
Haematologica. 2018 Apr;103(4):565-574. doi: 10.3324/haematol.2017.185603. Epub 2018 Mar 8.
Haematologica. 2018.
PMID: 29519871
Free PMC article.
Review.
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Tumor suppressor IKZF1 mediates glucocorticoid resistance in B-cell precursor acute lymphoblastic leukemia.
Marke R, Havinga J, Cloos J, Demkes M, Poelmans G, Yuniati L, van Ingen Schenau D, Sonneveld E, Waanders E, Pieters R, Kuiper RP, Hoogerbrugge PM, Kaspers GJ, van Leeuwen FN, Scheijen B.
Marke R, et al.
Leukemia. 2016 Jul;30(7):1599-603. doi: 10.1038/leu.2015.359. Epub 2015 Dec 29.
Leukemia. 2016.
PMID: 26713593
No abstract available.
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Reversal of IKZF1-induced glucocorticoid resistance by dual targeting of AKT and ERK signaling pathways.
Butler M, Vervoort BMT, van Ingen Schenau DS, Jongeneel L, van der Zwet JCG, Marke R, Meijerink JPP, Scheijen B, van der Meer LT, van Leeuwen FN.
Butler M, et al. Among authors: marke r.
Front Oncol. 2022 Sep 2;12:905665. doi: 10.3389/fonc.2022.905665. eCollection 2022.
Front Oncol. 2022.
PMID: 36119546
Free PMC article.
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