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Frontrunners in the race to develop a SARS-CoV-2 vaccine.
Russell RL, Pelka P, Mark BL. Russell RL, et al. Among authors: mark bl. Can J Microbiol. 2021 Mar;67(3):189-212. doi: 10.1139/cjm-2020-0465. Epub 2020 Dec 2. Can J Microbiol. 2021. PMID: 33264067 Free article. Review.
Crystal structure of the Middle East respiratory syndrome coronavirus (MERS-CoV) papain-like protease bound to ubiquitin facilitates targeted disruption of deubiquitinating activity to demonstrate its role in innate immune suppression.
Bailey-Elkin BA, Knaap RC, Johnson GG, Dalebout TJ, Ninaber DK, van Kasteren PB, Bredenbeek PJ, Snijder EJ, Kikkert M, Mark BL. Bailey-Elkin BA, et al. Among authors: mark bl. J Biol Chem. 2014 Dec 12;289(50):34667-82. doi: 10.1074/jbc.M114.609644. Epub 2014 Oct 15. J Biol Chem. 2014. PMID: 25320088 Free PMC article.
Potent and selective inhibition of pathogenic viruses by engineered ubiquitin variants.
Zhang W, Bailey-Elkin BA, Knaap RCM, Khare B, Dalebout TJ, Johnson GG, van Kasteren PB, McLeish NJ, Gu J, He W, Kikkert M, Mark BL, Sidhu SS. Zhang W, et al. Among authors: mark bl. PLoS Pathog. 2017 May 18;13(5):e1006372. doi: 10.1371/journal.ppat.1006372. eCollection 2017 May. PLoS Pathog. 2017. PMID: 28542609 Free PMC article.
Demonstrating the importance of porcine reproductive and respiratory syndrome virus papain-like protease 2 deubiquitinating activity in viral replication by structure-guided mutagenesis.
Bailey-Elkin BA, Knaap RCM, De Silva A, Boekhoud IM, Mous S, van Vught N, Khajehpour M, van den Born E, Kikkert M, Mark BL. Bailey-Elkin BA, et al. Among authors: mark bl. PLoS Pathog. 2023 Dec 14;19(12):e1011872. doi: 10.1371/journal.ppat.1011872. eCollection 2023 Dec. PLoS Pathog. 2023. PMID: 38096325 Free PMC article.
Structure and Function of Viral Deubiquitinating Enzymes.
Bailey-Elkin BA, Knaap RCM, Kikkert M, Mark BL. Bailey-Elkin BA, et al. Among authors: mark bl. J Mol Biol. 2017 Nov 10;429(22):3441-3470. doi: 10.1016/j.jmb.2017.06.010. Epub 2017 Jun 16. J Mol Biol. 2017. PMID: 28625850 Free PMC article. Review.
Letter to the Editor.
Mark BL, Mahuran D. Mark BL, et al. Mol Ther. 2021 Jan 6;29(1):3. doi: 10.1016/j.ymthe.2020.12.006. Epub 2020 Dec 11. Mol Ther. 2021. PMID: 33321097 Free PMC article. No abstract available.
71 results