Mariuzza RA - Search Results

1

Structure of engineered hepatitis C virus E1E2 ectodomain in complex with neutralizing antibodies.

Metcalf MC, Janus BM, Yin R, Wang R, Guest JD, Pozharski E, Law M, Mariuzza RA, Toth EA, Pierce BG, Fuerst TR, Ofek G. Metcalf MC, et al. Among authors: mariuzza ra. Nat Commun. 2023 Jul 5;14(1):3980. doi: 10.1038/s41467-023-39659-z. Nat Commun. 2023. PMID: 37407593 Free PMC article.

2

Structural basis for penetration of the glycan shield of hepatitis C virus E2 glycoprotein by a broadly neutralizing human antibody.

Li Y, Pierce BG, Wang Q, Keck ZY, Fuerst TR, Foung SK, Mariuzza RA. Li Y, et al. Among authors: mariuzza ra. J Biol Chem. 2015 Apr 17;290(16):10117-25. doi: 10.1074/jbc.M115.643528. Epub 2015 Mar 3. J Biol Chem. 2015. PMID: 25737449 Free PMC article.

3

Structural Basis for Clonal Diversity of the Public T Cell Response to a Dominant Human Cytomegalovirus Epitope.

Yang X, Gao M, Chen G, Pierce BG, Lu J, Weng NP, Mariuzza RA. Yang X, et al. Among authors: mariuzza ra. J Biol Chem. 2015 Nov 27;290(48):29106-19. doi: 10.1074/jbc.M115.691311. Epub 2015 Oct 1. J Biol Chem. 2015. PMID: 26429912 Free PMC article. Clinical Trial.

4

Affinity maturation of a broadly neutralizing human monoclonal antibody that prevents acute hepatitis C virus infection in mice.

Keck ZY, Wang Y, Lau P, Lund G, Rangarajan S, Fauvelle C, Liao GC, Holtsberg FW, Warfield KL, Aman MJ, Pierce BG, Fuerst TR, Bailey JR, Baumert TF, Mariuzza RA, Kneteman NM, Foung SK. Keck ZY, et al. Among authors: mariuzza ra. Hepatology. 2016 Dec;64(6):1922-1933. doi: 10.1002/hep.28850. Epub 2016 Oct 28. Hepatology. 2016. PMID: 27641232 Free PMC article.

5

Global mapping of antibody recognition of the hepatitis C virus E2 glycoprotein: Implications for vaccine design.

Pierce BG, Keck ZY, Lau P, Fauvelle C, Gowthaman R, Baumert TF, Fuerst TR, Mariuzza RA, Foung SKH. Pierce BG, et al. Among authors: mariuzza ra. Proc Natl Acad Sci U S A. 2016 Nov 8;113(45):E6946-E6954. doi: 10.1073/pnas.1614942113. Epub 2016 Oct 26. Proc Natl Acad Sci U S A. 2016. PMID: 27791171 Free PMC article.

6

Peptide-MHC (pMHC) binding to a human antiviral T cell receptor induces long-range allosteric communication between pMHC- and CD3-binding sites.

Rangarajan S, He Y, Chen Y, Kerzic MC, Ma B, Gowthaman R, Pierce BG, Nussinov R, Mariuzza RA, Orban J. Rangarajan S, et al. Among authors: mariuzza ra. J Biol Chem. 2018 Oct 12;293(41):15991-16005. doi: 10.1074/jbc.RA118.003832. Epub 2018 Aug 22. J Biol Chem. 2018. PMID: 30135211 Free PMC article.

7

Antigenicity and Immunogenicity of Differentially Glycosylated Hepatitis C Virus E2 Envelope Proteins Expressed in Mammalian and Insect Cells.

Urbanowicz RA, Wang R, Schiel JE, Keck ZY, Kerzic MC, Lau P, Rangarajan S, Garagusi KJ, Tan L, Guest JD, Ball JK, Pierce BG, Mariuzza RA, Foung SKH, Fuerst TR. Urbanowicz RA, et al. Among authors: mariuzza ra. J Virol. 2019 Mar 21;93(7):e01403-18. doi: 10.1128/JVI.01403-18. Print 2019 Apr 1. J Virol. 2019. PMID: 30651366 Free PMC article.

8

Structural basis for oligoclonal T cell recognition of a shared p53 cancer neoantigen.

Wu D, Gallagher DT, Gowthaman R, Pierce BG, Mariuzza RA. Wu D, et al. Among authors: mariuzza ra. Nat Commun. 2020 Jun 9;11(1):2908. doi: 10.1038/s41467-020-16755-y. Nat Commun. 2020. PMID: 32518267 Free PMC article.

9

In Vivo and In Vitro Potency of Polyphosphazene Immunoadjuvants with Hepatitis C Virus Antigen and the Role of Their Supramolecular Assembly.

Andrianov AK, Marin A, Wang R, Chowdhury A, Agnihotri P, Yunus AS, Pierce BG, Mariuzza RA, Fuerst TR. Andrianov AK, et al. Among authors: mariuzza ra. Mol Pharm. 2021 Feb 1;18(2):726-734. doi: 10.1021/acs.molpharmaceut.0c00487. Epub 2020 Jun 23. Mol Pharm. 2021. PMID: 32530637 Free PMC article.

10

Structure-Based Design of Hepatitis C Virus E2 Glycoprotein Improves Serum Binding and Cross-Neutralization.

Pierce BG, Keck ZY, Wang R, Lau P, Garagusi K, Elkholy K, Toth EA, Urbanowicz RA, Guest JD, Agnihotri P, Kerzic MC, Marin A, Andrianov AK, Ball JK, Mariuzza RA, Fuerst TR, Foung SKH. Pierce BG, et al. Among authors: mariuzza ra. J Virol. 2020 Oct 27;94(22):e00704-20. doi: 10.1128/JVI.00704-20. Print 2020 Oct 27. J Virol. 2020. PMID: 32878891 Free PMC article.

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