Marini AM - Search Results

1

Naphtho[1,2-d]isothiazole acetic acid derivatives as a novel class of selective aldose reductase inhibitors.

Da Settimo F, Primofiore G, La Motta C, Sartini S, Taliani S, Simorini F, Marini AM, Lavecchia A, Novellino E, Boldrini E. Da Settimo F, et al. Among authors: marini am. J Med Chem. 2005 Nov 3;48(22):6897-907. doi: 10.1021/jm050382p. J Med Chem. 2005. PMID: 16250648

2

Tricyclic sulfonamides incorporating benzothiopyrano[4,3-c]pyrazole and pyridothiopyrano[4,3-c]pyrazole effectively inhibit α- and β-carbonic anhydrase: X-ray crystallography and solution investigations on 15 isoforms.

Marini AM, Maresca A, Aggarwal M, Orlandini E, Nencetti S, Da Settimo F, Salerno S, Simorini F, La Motta C, Taliani S, Nuti E, Scozzafava A, McKenna R, Rossello A, Supuran CT. Marini AM, et al. J Med Chem. 2012 Nov 26;55(22):9619-29. doi: 10.1021/jm300878g. Epub 2012 Nov 8. J Med Chem. 2012. PMID: 23067387

3

Novel, highly potent adenosine deaminase inhibitors containing the pyrazolo[3,4-d]pyrimidine ring system. Synthesis, structure-activity relationships, and molecular modeling studies.

Da Settimo F, Primofiore G, La Motta C, Taliani S, Simorini F, Marini AM, Mugnaini L, Lavecchia A, Novellino E, Tuscano D, Martini C. Da Settimo F, et al. Among authors: marini am. J Med Chem. 2005 Aug 11;48(16):5162-74. doi: 10.1021/jm050136d. J Med Chem. 2005. PMID: 16078836

4

Refinement of the benzodiazepine receptor site topology by structure-activity relationships of new N-(heteroarylmethyl)indol-3-ylglyoxylamides.

Primofiore G, Da Settimo F, Marini AM, Taliani S, La Motta C, Simorini F, Novellino E, Greco G, Cosimelli B, Ehlardo M, Sala A, Besnard F, Montali M, Martini C. Primofiore G, et al. Among authors: marini am. J Med Chem. 2006 Apr 20;49(8):2489-95. doi: 10.1021/jm0511841. J Med Chem. 2006. PMID: 16610792

5

Novel N-substituted indol-3-ylglyoxylamides probing the LDi and L1/L2 lipophilic regions of the benzodiazepine receptor site in search for subtype-selective ligands.

Primofiore G, Taliani S, Da Settimo F, Marini AM, La Motta C, Simorini F, Patrizi MP, Sergianni V, Novellino E, Greco G, Cosimelli B, Calderone V, Montali M, Besnard F, Martini C. Primofiore G, et al. Among authors: marini am. J Med Chem. 2007 Apr 5;50(7):1627-34. doi: 10.1021/jm0607707. Epub 2007 Mar 3. J Med Chem. 2007. PMID: 17335185

6

Pyrido[1,2-a]pyrimidin-4-one derivatives as a novel class of selective aldose reductase inhibitors exhibiting antioxidant activity.

La Motta C, Sartini S, Mugnaini L, Simorini F, Taliani S, Salerno S, Marini AM, Da Settimo F, Lavecchia A, Novellino E, Cantore M, Failli P, Ciuffi M. La Motta C, et al. Among authors: marini am. J Med Chem. 2007 Oct 4;50(20):4917-27. doi: 10.1021/jm070398a. Epub 2007 Sep 11. J Med Chem. 2007. PMID: 17845019

7

5-amino-2-phenyl[1,2,3]triazolo[1,2-a][1,2,4]benzotriazin-1-one: a versatile scaffold to obtain potent and selective A3 adenosine receptor antagonists.

Da Settimo F, Primofiore G, Taliani S, Marini AM, La Motta C, Simorini F, Salerno S, Sergianni V, Tuccinardi T, Martinelli A, Cosimelli B, Greco G, Novellino E, Ciampi O, Trincavelli ML, Martini C. Da Settimo F, et al. Among authors: marini am. J Med Chem. 2007 Nov 15;50(23):5676-84. doi: 10.1021/jm0708376. Epub 2007 Oct 10. J Med Chem. 2007. PMID: 17927167

8

Acetic acid aldose reductase inhibitors bearing a five-membered heterocyclic core with potent topical activity in a visual impairment rat model.

La Motta C, Sartini S, Salerno S, Simorini F, Taliani S, Marini AM, Da Settimo F, Marinelli L, Limongelli V, Novellino E. La Motta C, et al. Among authors: marini am. J Med Chem. 2008 Jun 12;51(11):3182-93. doi: 10.1021/jm701613h. Epub 2008 May 2. J Med Chem. 2008. PMID: 18452283

9

Exploiting the pyrazolo[3,4-d]pyrimidin-4-one ring system as a useful template to obtain potent adenosine deaminase inhibitors.

La Motta C, Sartini S, Mugnaini L, Salerno S, Simorini F, Taliani S, Marini AM, Da Settimo F, Lavecchia A, Novellino E, Antonioli L, Fornai M, Blandizzi C, Del Tacca M. La Motta C, et al. Among authors: marini am. J Med Chem. 2009 Mar 26;52(6):1681-92. doi: 10.1021/jm801427r. J Med Chem. 2009. PMID: 19226143

10

Identification of anxiolytic/nonsedative agents among indol-3-ylglyoxylamides acting as functionally selective agonists at the gamma-aminobutyric acid-A (GABAA) alpha2 benzodiazepine receptor.

Taliani S, Cosimelli B, Da Settimo F, Marini AM, La Motta C, Simorini F, Salerno S, Novellino E, Greco G, Cosconati S, Marinelli L, Salvetti F, L'Abbate G, Trasciatti S, Montali M, Costa B, Martini C. Taliani S, et al. Among authors: marini am. J Med Chem. 2009 Jun 25;52(12):3723-34. doi: 10.1021/jm9001154. J Med Chem. 2009. PMID: 19469479

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