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IL-13/IL-4 signaling contributes to fibrotic progression of the myeloproliferative neoplasms.
Melo-Cardenas J, Bezavada L, Crawford JC, Gurbuxani S, Cotton A, Kang G, Gossett J, Marinaccio C, Weinberg R, Hoffman R, Migliaccio AR, Zheng Y, Derecka M, Rinaldi CR, Crispino JD. Melo-Cardenas J, et al. Among authors: marinaccio c. Blood. 2022 Dec 29;140(26):2805-2817. doi: 10.1182/blood.2022017326. Blood. 2022. PMID: 36283106 Free PMC article.
LKB1/STK11 Is a Tumor Suppressor in the Progression of Myeloproliferative Neoplasms.
Marinaccio C, Suraneni P, Celik H, Volk A, Wen QJ, Ling T, Bulic M, Lasho T, Koche RP, Famulare CA, Farnoud N, Stein B, Schieber M, Gurbuxani S, Root DE, Younger ST, Hoffman R, Gangat N, Ntziachristos P, Chandel NS, Levine RL, Rampal RK, Challen GA, Tefferi A, Crispino JD. Marinaccio C, et al. Cancer Discov. 2021 Jun;11(6):1398-1410. doi: 10.1158/2159-8290.CD-20-1353. Epub 2021 Feb 12. Cancer Discov. 2021. PMID: 33579786 Free PMC article.
Resident Self-Tissue of Proinflammatory Cytokines Rather Than Their Systemic Levels Correlates with Development of Myelofibrosis in Gata1low Mice.
Zingariello M, Verachi P, Gobbo F, Martelli F, Falchi M, Mazzarini M, Valeri M, Sarli G, Marinaccio C, Melo-Cardenas J, Crispino JD, Migliaccio AR. Zingariello M, et al. Among authors: marinaccio c. Biomolecules. 2022 Jan 30;12(2):234. doi: 10.3390/biom12020234. Biomolecules. 2022. PMID: 35204735 Free PMC article.
Activation of JAK/STAT Signaling in Megakaryocytes Sustains Myeloproliferation In Vivo.
Woods B, Chen W, Chiu S, Marinaccio C, Fu C, Gu L, Bulic M, Yang Q, Zouak A, Jia S, Suraneni PK, Xu K, Levine RL, Crispino JD, Wen QJ. Woods B, et al. Among authors: marinaccio c. Clin Cancer Res. 2019 Oct 1;25(19):5901-5912. doi: 10.1158/1078-0432.CCR-18-4089. Epub 2019 Jun 19. Clin Cancer Res. 2019. PMID: 31217200 Free PMC article.
AKT activation is a feature of CALR mutant myeloproliferative neoplasms.
Fu C, Wen QJ, Marinaccio C, Ling T, Chen W, Bulic M, Lasho T, Tefferi A, Crispino JD, Xu K. Fu C, et al. Among authors: marinaccio c. Leukemia. 2019 Jan;33(1):271-274. doi: 10.1038/s41375-018-0224-8. Epub 2018 Aug 6. Leukemia. 2019. PMID: 30082822 Free PMC article. No abstract available.
Aurora Kinase A Inhibition Provides Clinical Benefit, Normalizes Megakaryocytes, and Reduces Bone Marrow Fibrosis in Patients with Myelofibrosis: A Phase I Trial.
Gangat N, Marinaccio C, Swords R, Watts JM, Gurbuxani S, Rademaker A, Fought AJ, Frankfurt O, Altman JK, Wen QJ, Farnoud N, Famulare CA, Patel A, Tapia R, Vallapureddy RR, Barath S, Graf A, Handlogten A, Zblewski D, Patnaik MM, Al-Kali A, Dinh YT, Englund Prahl K, Patel S, Nobrega JC, Tejera D, Thomassen A, Gao J, Ji P, Rampal RK, Giles FJ, Tefferi A, Stein B, Crispino JD. Gangat N, et al. Among authors: marinaccio c. Clin Cancer Res. 2019 Aug 15;25(16):4898-4906. doi: 10.1158/1078-0432.CCR-19-1005. Epub 2019 May 6. Clin Cancer Res. 2019. PMID: 31061068
36 results