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Mitochondrial dysfunction in human hypertrophic cardiomyopathy is linked to cardiomyocyte architecture disruption and corrected by improving NADH-driven mitochondrial respiration.
Nollet EE, Duursma I, Rozenbaum A, Eggelbusch M, Wüst RCI, Schoonvelde SAC, Michels M, Jansen M, van der Wel NN, Bedi KC, Margulies KB, Nirschl J, Kuster DWD, van der Velden J. Nollet EE, et al. Among authors: margulies kb. Eur Heart J. 2023 Apr 1;44(13):1170-1185. doi: 10.1093/eurheartj/ehad028. Eur Heart J. 2023. PMID: 36734059 Free PMC article.
Mitochondrial protein hyperacetylation in the failing heart.
Horton JL, Martin OJ, Lai L, Riley NM, Richards AL, Vega RB, Leone TC, Pagliarini DJ, Muoio DM, Bedi KC Jr, Margulies KB, Coon JJ, Kelly DP. Horton JL, et al. Among authors: margulies kb. JCI Insight. 2016 Feb;2(1):e84897. doi: 10.1172/jci.insight.84897. Epub 2016 Feb 25. JCI Insight. 2016. PMID: 26998524 Free PMC article.
C-type natriuretic peptide co-ordinates cardiac structure and function.
Moyes AJ, Chu SM, Aubdool AA, Dukinfield MS, Margulies KB, Bedi KC, Hodivala-Dilke K, Baliga RS, Hobbs AJ. Moyes AJ, et al. Among authors: margulies kb. Eur Heart J. 2020 Mar 1;41(9):1006-1020. doi: 10.1093/eurheartj/ehz093. Eur Heart J. 2020. PMID: 30903134 Free PMC article.
Repurposing an anti-cancer agent for the treatment of hypertrophic heart disease.
Dukinfield M, Maniati E, Reynolds LE, Aubdool A, Baliga RS, D'Amico G, Maiques O, Wang J, Bedi KC Jr, Margulies KB, Sanz-Moreno V, Hobbs A, Hodivala-Dilke K. Dukinfield M, et al. Among authors: margulies kb. J Pathol. 2019 Dec;249(4):523-535. doi: 10.1002/path.5340. Epub 2019 Oct 30. J Pathol. 2019. PMID: 31424556 Free PMC article.
Noncanonical WNT Activation in Human Right Ventricular Heart Failure.
Edwards JJ, Brandimarto J, Hu DQ, Jeong S, Yucel N, Li L, Bedi KC Jr, Wada S, Murashige D, Hwang HTV, Zhao M, Margulies KB, Bernstein D, Reddy S, Arany Z. Edwards JJ, et al. Among authors: margulies kb. Front Cardiovasc Med. 2020 Oct 7;7:582407. doi: 10.3389/fcvm.2020.582407. eCollection 2020. Front Cardiovasc Med. 2020. PMID: 33134326 Free PMC article.
Circadian Pattern of Ion Channel Gene Expression in Failing Human Hearts.
McTiernan CF, Lemster BH, Bedi KC, Margulies KB, Moravec CS, Hsieh PN, Shusterman V, Saba S. McTiernan CF, et al. Among authors: margulies kb. Circ Arrhythm Electrophysiol. 2021 Jan;14(1):e009254. doi: 10.1161/CIRCEP.120.009254. Epub 2020 Dec 10. Circ Arrhythm Electrophysiol. 2021. PMID: 33301345 Free PMC article.
287 results