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SUMOylation of SAMHD1 at Lysine 595 is required for HIV-1 restriction in non-cycling cells.
Martinat C, Cormier A, Tobaly-Tapiero J, Palmic N, Casartelli N, Mahboubi B, Coggins SA, Buchrieser J, Persaud M, Diaz-Griffero F, Espert L, Bossis G, Lesage P, Schwartz O, Kim B, Margottin-Goguet F, Saïb A, Zamborlini A. Martinat C, et al. Among authors: margottin goguet f. Nat Commun. 2021 Jul 28;12(1):4582. doi: 10.1038/s41467-021-24802-5. Nat Commun. 2021. PMID: 34321470 Free PMC article.
SAMHD1 restricts the replication of human immunodeficiency virus type 1 by depleting the intracellular pool of deoxynucleoside triphosphates.
Lahouassa H, Daddacha W, Hofmann H, Ayinde D, Logue EC, Dragin L, Bloch N, Maudet C, Bertrand M, Gramberg T, Pancino G, Priet S, Canard B, Laguette N, Benkirane M, Transy C, Landau NR, Kim B, Margottin-Goguet F. Lahouassa H, et al. Nat Immunol. 2012 Feb 12;13(3):223-228. doi: 10.1038/ni.2236. Nat Immunol. 2012. PMID: 22327569 Free PMC article.
HIV-1 Vpr degrades the HLTF DNA translocase in T cells and macrophages.
Lahouassa H, Blondot ML, Chauveau L, Chougui G, Morel M, Leduc M, Guillonneau F, Ramirez BC, Schwartz O, Margottin-Goguet F. Lahouassa H, et al. Proc Natl Acad Sci U S A. 2016 May 10;113(19):5311-6. doi: 10.1073/pnas.1600485113. Epub 2016 Apr 25. Proc Natl Acad Sci U S A. 2016. PMID: 27114546 Free PMC article.
Binding to DCAF1 distinguishes TASOR and SAMHD1 degradation by HIV-2 Vpx.
Martin MM, Matkovic R, Larrous P, Morel M, Lasserre A, Vauthier V, Margottin-Goguet F. Martin MM, et al. Among authors: margottin goguet f. PLoS Pathog. 2021 Oct 26;17(10):e1009609. doi: 10.1371/journal.ppat.1009609. eCollection 2021 Oct. PLoS Pathog. 2021. PMID: 34699574 Free PMC article.
TASOR epigenetic repressor cooperates with a CNOT1 RNA degradation pathway to repress HIV.
Matkovic R, Morel M, Lanciano S, Larrous P, Martin B, Bejjani F, Vauthier V, Hansen MMK, Emiliani S, Cristofari G, Gallois-Montbrun S, Margottin-Goguet F. Matkovic R, et al. Among authors: margottin goguet f. Nat Commun. 2022 Jan 10;13(1):66. doi: 10.1038/s41467-021-27650-5. Nat Commun. 2022. PMID: 35013187 Free PMC article.
40 results